общая химия (страница 5)

Автор: Группа авторов

The first comprehensive account of the rapidly growing field of asymmetric dearomatization reactions with a focus on catalytic methods. It introduces the concept of dearomatization and describes recent progress in asymmetric reaction procedures with different catalyst systems, such as organocatalysts, transition metal catalysts, and enzymes. Chapters on dearomatizations of electron-deficient aromatic rings, dearomatization reactions via transition metal-catalyzed cross-couplings as well as dearomatization strategies in the synthesis of complex natural products are also included. Written by pioneers in the field, this is a highly valuable source of information not only for professional synthetic chemists in academia and industry but also for all those are interested in asymmetric methodologies and organic synthesis in general.

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Автор: Liu-Zhu Gong

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Автор: Christofer Leygraf

Presents a comprehensive look at atmospheric corrosion, combining expertise in corrosion science and atmospheric chemistry Is an invaluable resource for corrosion scientists, corrosion engineers, and anyone interested in the theory and application of Atmospheric Corrosion Updates and expands topics covered to include, international exposure programs and the environmental effects of atmospheric corrosion Covers basic principles and theory of atmospheric corrosion chemistry as well as corrosion mechanisms in controlled and uncontrolled environments Details degradation of materials in architectural and structural applications, electronic devices, and cultural artifacts Includes appendices with data on specific materials, experimental techniques, atmospheric species

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Автор: Группа авторов

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Автор: AICPA

The 2017 edition of this industry standard resource offers clear and practical guidance of audit and accounting issues such as transfers and servicing, troubled debt restructurings, financing receivables and the allowance for loan losses, and fair value accounting. It also provides direction for institutions assessing their operations and internal controls for regulatory considerations as well as discussions on existing regulatory reporting matters. Updates include: SAS No. 132, The Auditor's Consideration of an Entity’s Ability to Continue as a Going Concern SSAE No. 18, Attestation Standards: Clarification and Recodification Note: FASB ASU No. 2016-13 will have a significant impact on the guide; however, incorporation of guidance will not occur until the 2018 or 2019 edition of the guide.

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Автор: Roseann M. Benson

In the last decade DNA sequencing costs have decreased over a magnitude, largely because of increasing throughput by incremental advances in tools, technologies and process improvements. Further cost reductions in this and in related proteomics technologies are expected as a result of the development of new high-throughput techniques and the computational machinery needed to analyze data generated. Automation in Proteomics & Genomics: An Engineering Case-Based Approach describes the automation technology currently in the areas of analysis, design, and integration, as well as providing basic biology concepts behind proteomics and genomics. The book also discusses the current technological limitations that can be viewed as an emerging market rather than a research bottleneck. Topics covered include: molecular biology fundamentals: from ‘blueprint’ (DNA) to ‘task list’ (RNA) to ‘molecular machine’ (protein); proteomics methods and technologies; modelling protein networks and interactions analysis via automation: DNA sequencing; microarrays and other parallelization technologies; protein characterization and identification; protein interaction and gene regulatory networks design via automation: DNA synthesis; RNA by design; building protein libraries; synthetic networks integration: multiple modalities; computational and experimental methods; trends in automation for genomics and proteomics new enabling technologies and future applications Automation in Proteomics & Genomics: An Engineering Case-Based Approach is an essential guide to the current capabilities and challenges of high-throughput analysis of genes and proteins for bioinformaticians, engineers, chemists, and biologists interested in developing a cross-discipline problem-solving based approach to systems biology.

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Автор: Группа авторов

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Автор: Harold M. McNair

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Автор: Germar M?ller

Grundlage der Berechnung elektrischer Maschinen ist das Verstandnis wesentlicher physikalischer Zusammenhange. Im zweiten Band der Reihe Elektrische Maschinen werden diese Zusammenhange schrittweise herausgearbeitet und analytisch formuliert. Das Lehrbuch stellt alle Werkzeuge bereit, die zur Berechnung rotierender elektrischer Maschinen benotigt werden. Es zeichnet sich durch eine fur die Buchreihe Elektrische Maschinen typische einheitliche und geschlossene Darstellungsweise aus. Das erste Kapitel widmet sich ausfuhrlich den Wicklungen elektrischer Maschinen, und in den Kapiteln 2 bis 8 werden die weiteren Elemente und Effekte vorgestellt, die in allen Maschinenarten vorkommen. Mit diesem 'Baukasten' wird anschlie?end der komplette Entwurfs- und Berechnungsgang wichtiger Maschinenarten behandelt. Dabei werden typische Anforderungen aus der Praxis und Optimierungsfragen ausfuhrlich berucksichtigt. Dieses Handbuch ist unentbehrlich fur die Berechnungspraxis und eine wertvolle Informationsquelle fur jeden Entwicklungsingenieur, der mit dem Entwurf elektrischer Maschinen befasst ist.

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Автор: G. K. Surya Prakash

The world is currently consuming about 85 million barrels of oil a day, and about two-thirds as much natural gas equivalent, both derived from non-renewable natural sources. In the foreseeable future, our energy needs will come from any available alternate source. Methanol is one such viable alternative, and also offers a convenient solution for efficient energy storage on a large scale. In this updated and enlarged edition, renowned chemists discuss in a clear and readily accessible manner the pros and cons of humankind's current main energy sources, while providing new ways to overcome obstacles. Following an introduction, the authors look at the interrelationship of fuels and energy, and at the extent of our non-renewable fossil fuels. They also discuss the hydrogen economy and its significant shortcomings. The main focus is on the conversion of CO2 from industrial as well as natural sources into liquid methanol and related DME, a diesel fuel substitute that can replace LNG and LPG. The book is rounded off with an optimistic look at future possibilities. A forward-looking and inspiring work that vividly illustrates potential solutions to our energy and environmental problems.

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Автор: Charles Green

This innovative new history examines in-depth how the growing popularity of large-scale international survey exhibitions, or 'biennials', has influenced global contemporary art since the 1950s. Provides a comprehensive global history of biennialization from the rise of the European star-curator in the 1970s to the emergence of mega-exhibitions in Asia in the 1990s Introduces a global array of case studies to illustrate the trajectory of biennials and their growing influence on artistic expression, from the Biennale de la M?diterran?e in Alexandria, Egypt in 1955, the second Havana Biennial of 1986, New York’s Whitney Biennial in 1993, and the 2002 Documenta11 in Kassel, to the Gwangju Biennale of 2014 Explores the evolving curatorial approaches to biennials, including analysis of the roles of sponsors, philanthropists and biennial directors and their re-shaping of the contemporary art scene Uses the history of biennials as a means of illustrating and inciting further discussions of globalization in contemporary art

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Автор: Группа авторов

Recent technological advances have provided unique opportunities for the exploration of alternatives to the industrial use of chemically produced synthetic colors. The most promising developments in this area have been in bio-pigmentation derived from microorganisms. This groundbreaking book reviews the current state of the science of bio-pigmentation, providing important insights into the molecular mechanisms of microbial biosynthesis of industrial pigments. Featuring contributions by leading researchers from both industry and academe, it explores the latest advances in the use of bio-pigments as safe, sustainable alternatives to chemically synthesized pigments, and provides extensive coverage the most promising sources of bio-pigments within the food, feed, and pharmaceutical industries. • Proposes microbial uniqueness of coloration in variety of food, feed and pharmaceuticals • Covers the basic science behind bio-pigmentation as well as the latest advances in the field • Describes detection strategies for screening and identifying color producing microorganisms under varying environmental conditions • Provides an exhaustive review of the literature on color producing extremophiles and offers fascinating insights into color production as a stress response in extremophiles • Explores microbial molecular mechanisms of color production, with special coverage of color production as secondary metabolites under environmental stress Bio-pigmentation and Biotechnological Implementations is required reading for professionals and post-doctoral students of microbiology, applied microbiology, food microbiology, food science, and food biochemistry. It is a valuable working resource for scientists working in color-dependent food, feed, and pharmaceuticals.

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Автор: Klaus Buchholz

This second edition of a bestselling textbook offers an instructive and comprehensive overview of our current knowledge of biocatalysis and enzyme technology. The book now contains about 40% more printed content. Three chapters are completely new, while the others have been thoroughly updated, and a section with problems and solutions as well as new case studies have been added. Following an introduction to the history of enzyme applications, the text goes on to cover in depth enzyme mechanisms and kinetics, production, recovery, characterization and design by protein engineering. The authors treat a broad range of applications of soluble and immobilized biocatalysts, including wholecell systems, the use of non-aqueous reaction systems, applications in organic synthesis, bioreactor design and reaction engineering. Methods to estimate the sustainability, important internet resources and their evaluation, and legislation concerning the use of biocatalysts are also covered.

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Автор: Robert B. Heimann

Reflecting the progress in recent years, this book provides in-depth information on the preparation, chemistry, and engineering of bioceramic coatings for medical implants. It is authored by two renowned experts with over 30 years of experience in industry and academia, who know the potentials and pitfalls of the techniques concerned. Following an introduction to the principles of biocompatibility, they present the structures and properties of various bioceramics from alumina to zirconia. The main part of the work focuses on coating technologies, such as chemical vapor deposition, sol-gel deposition and thermal spraying. There then follows a discussion of the major interactions of bioceramics with bone or tissue cells, complemented by an overview of the in-vitro testing methods of the biomineralization properties of bioceramics. The text is rounded off by chapters on the functionalization of bioceramic coatings and a look at future trends. As a result, the authors bring together all aspects of the latest techniques for designing, depositing, testing, and implementing improved and novel bioceramic coating compositions, providing a full yet concise overview for beginners and professionals.

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Автор: Rolando Guidelli

Invaluable to biochemists, biophysicists, and pharmacological scientists; this book provides insights into the essential principles required to understand why and how electrochemical and electrophysiological tools are fundamental in elucidating the mode of ion transport across biomembranes. • Describes the essential electrochemical basics required to understand why and how electrochemical and electrophysiological tools are fundamental in elucidating the mode of ion transport across biomembranes • Requires only basic physical chemistry and mathematics to be understood, without intermediate stumbling blocks that would discourage the reader from proceeding further • Develops contents in a step-by-step approach that encourages students and researchers to read from beginning to end

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Автор: Группа авторов

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Автор: Группа авторов

With increased public and scientific attention driven by factors such as oil price spikes, the need for increased energy security, and concerns over greenhouse gas emissions from fossil fuels, the production of fuels by biological systems is becoming increasingly important as the world seeks to move towards renewable, sustainable energy sources. Biofuels and Bioenergy presents a broad, wide-ranging and informative treatment of biofuels. The book covers historical, economic, industrial, sociological and ecological/environmental perspectives as well as dealing with all the major scientific issues associated with this important topic. With contributions from a range of leading experts covering key aspects, including: • Conventional biofuels. • Basic biology, biochemistry and chemistry of different types and classes of biofuel. • Current research in synthetic biology and GM in the development and exploitation of new biofuel sources. • Aspects relating to ecology and land use, including the fuel v food dilemma. • Sustainability of different types of biofuel. • Ethical aspects of biofuel production. Biofuels and Bioenergy provides students and researchers in biology, chemistry, biochemistry and chemical engineering with an accessible review of this increasingly important subject.

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Автор: Michael Boot

Written by experts in combustion technology, this is a unique and refreshing perspective on the current biofuel discussion, presenting the latest research in this important field. The emphasis throughout this reference is on applications, industrial perspectives and economics, focusing on new classes of biofuels such as butanols, levulinates, benzenoids and others. Clearly structured, each chapter presents a new class of biofuel and discusses such topics as production pathways, fuel properties and its impact on engines. The result is a fascinating, user-oriented overview of new classes of biofuels beyond bioethanol.

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Автор: Группа авторов

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Автор: Rene Fester Kratz

Biology Essentials For Dummies (9781119589587) was previously published as Biology Essentials For Dummies (9781118072677). While this version features a new Dummies cover and design, the content is the same as the prior release and should not be considered a new or updated product. Just the core concepts you need to score high in your biology course Biology Essentials For Dummies focuses on just the core concepts you need to succeed in an introductory biology course. From identifying the structures and functions of plants and animals to grasping the crucial discoveries in evolutionary, reproductive, and ecological biology, this easy-to-follow guide lets you skip the suffering and score high at exam time. Get down to basics – master the fundamentals, from understanding what biologists study to how living things are classified The chemistry of life – find out what you need to know about atoms, elements, molecules, compounds, acids, bases, and more Conquer and divide – discover the ins and outs of asexual and sexual reproduction, including cell division and DNA replication Jump into the gene pool – grasp how proteins make traits happen, and easily understand DNA transcription, RNA processing, translation, and gene regulation.

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Автор: Группа авторов

Focusing on the key challenges that still impede the realization of the billion-ton renewable fuels vision, this book integrates technological development and business development rationales to highlight the key technological.developments that are necessary to industrialize biofuels on a global scale. Technological issues addressed in this work include fermentation and downstream processing technologies, as compared to current industrial practice and process economics. Business issues that provide the lens through which the technological review is performed span the entire biofuel value chain, from financial mechanisms to fund biotechnology start-ups in the biofuel arena up to large green field manufacturing projects, to raw material farming, collection and transport to the bioconversion plant, manufacturing, product recovery, storage, and transport to the point of sale. Emphasis has been placed throughout the book on providing a global view that takes into account the intrinsic characteristics of various biofuels markets from Brazil, the EU, the US, or Japan, to emerging economies as agricultural development and biofuel development appear undissociably linked.

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Автор: Группа авторов

Taking place at the David L. Lawrence Convention Center, Pittsburgh, Pennsylvania, this CT Volume contains 17 papers from the following 2014 Materials Science and Technology (MS&T'14) symposia: Next Generation Biomaterials Surface Properties of Biomaterials

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Автор: Группа авторов

At the interface of biology, chemistry, and materials science, this book provides an overview of this vibrant research field, treating the seemingly distinct disciplines in a unified way by adopting the common viewpoint of surface science. The editors, themselves prolific researchers, have assembled here a team of top-notch international scientists who read like a «who's who» of biomaterials science and engineering. They cover topics ranging from micro- and nanostructuring for imparting functionality in a top-down manner to the bottom-up fabrication of gradient surfaces by self-assembly, from interfaces between biomaterials and living matter to smart, stimuli-responsive surfaces, and from cell and surface mechanics to the elucidation of cell-chip interactions in biomedical devices. As a result, the book explains the complex interplay of cell behavior and the physics and materials science of artificial devices. Of equal interest to young, ambitious scientists as well as to experienced researchers.

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Автор: Abdelkhalak El Hami

In this book, the authors present in detail several recent methodologies and algorithms that they developed during the last fifteen years. The deterministic methods account for uncertainties through empirical safety factors, which implies that the actual uncertainties in materials, geometry and loading are not truly considered. This problem becomes much more complicated when considering biomechanical applications where a number of uncertainties are encountered in the design of prosthesis systems. This book implements improved numerical strategies and algorithms that can be applied to biomechanical studies.

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Автор: Группа авторов

Biomedical Devices: Design, Prototyping, and Manufacturing features fundamental discussions of all facets of materials processing and manufacturing processes across a wide range of medical devices and artificial tissues. Represents the first compilation of information on the design, prototyping, and manufacture of medical devices into one volume Offers in-depth coverage of medical devices, beginning with an introductory overview through to the design, manufacture, and applications Features examples of a variety of medical applications of devices, including biopsy micro forceps, micro-needle arrays, wrist implants, spinal spacers, and fixtures Provides students, doctors, scientists, and technicians interested in the development and applications of medical devices the ideal reference source

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Автор: Группа авторов

The functional materials with the most promising outlook have the ability to precisely adjust the biological phenomenon in a controlled mode. Engineering of advanced bio- materials has found striking applications in used for biomedical and diagnostic device applications, such as cell separation, stem-cell, drug delivery, hyperthermia, automated DNA extraction, gene targeting, resonance imaging, biosensors, tissue engineering and organ regeneration.

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Автор: Rangaraj M. Rangayyan

The book will help assist a reader in the development of techniques for analysis of biomedical signals and computer aided diagnoses with a pedagogical examination of basic and advanced topics accompanied by over 350 figures and illustrations. Wide range of filtering techniques presented to address various applications 800 mathematical expressions and equations Practical questions, problems and laboratory exercises Includes fractals and chaos theory with biomedical applications

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Автор: Группа авторов

Sets forth the techniques needed to create a vast array of useful biopolymer nanocomposites Interest in biopolymer nanocomposites is soaring. Not only are they green and sustainable materials, they can also be used to develop a broad range of useful products with special properties, from therapeutics to coatings to packaging materials. With contributions from an international team of leading nanoscientists and materials researchers, this book draws together and reviews the most recent developments and techniques in biopolymer nano-composites. It describes the preparation, processing, properties, and applications of bio- polymer nanocomposites developed from chitin, starch, and cellulose, three renewable resources. Biopolymer Nanocomposites features a logical organization and approach that make it easy for readers to take full advantage of the latest science and technology in designing these materials and developing new products and applications. It begins with a chapter reviewing our current understanding of bionanocomposites. Next, the book covers such topics as: Morphological and thermal investigations of chitin-based nanocomposites Applications of starch nanoparticle and starch-based bionanocomposites Spectroscopic characterization of renewable nanoparticles and their composites Nanocellulosic products and their applications Protein-based nanocomposites for food packaging Throughout the book, detailed case studies of industrial applications underscore the unique challenges and opportunities in developing and working with biopolymer nanocomposites. There are also plenty of figures to help readers fully grasp key concepts and techniques. Exploring the full range of applications, Biopolymer Nanocomposites is recommended for researchers in a broad range of industries and disciplines, including biomedical engineering, materials science, physical chemistry, chemical engineering, and polymer science. All readers will learn how to create green, sustainable products and applications using these tremendously versatile materials.

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Автор: Группа авторов

This book highlights the technical and methodological advancements in introducing biopolymers, their study and promoted applications. Organized in four parts, the book provides initially a general overview over biopolymers, properties and biocompatibility and continues with dedicated parts on ?Biopolyemrs through Bioengineering and Biotechnology Venues?, ?Polymeric Biomaterials with wide applications? and ?Biopolymers for Specific Applications?.

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Автор: Группа авторов

This book provides the vision of a successful biorefinery—the lignocelluloic biomass needs to be efficiently converted to its constituent monomers, comprising mainly of sugars such as glucose, xylose, mannose and arabinose. Accordingly, the first part of the book deals with aspects crucial for the pretreatment and hydrolysis of biomass to give sugars in high yield, as well as the general aspects of bioprocessing technologies which will enable the development of biorefineries through inputs of metabolic engineering, fermentation, downstream processing and formulation. The second part of the book gives the current status and future directions of the biological processes for production of ethanol (a biofuel as well as an important commodity raw material), solvents (butanol, isobutanol, butanediols, propanediols), organic acids (lactic acid, 3-hydroxy propionic acid, fumaric acid, succinic acid and adipic acid), and amino acid (glutamic acid). The commercial production of some of these commodity bioproducts in the near future will have a far reaching effect in realizing our goal of sustainable conversion of these renewable resources and realizing the concept of biorefinery. Suitable for researchers, practitioners, graduate students and consultants in biochemical/ bioprocess engineering, industrial microbiology, bioprocess technology, metabolic engineering, environmental science and energy, the book offers: Exemplifies the application of metabolic engineering approaches for development of microbial cell factories Provides a unique perspective to the industry about the scientific problems and their possible solutions in making a bioprocess work for commercial production of commodity bioproducts Discusses the processing of renewable resources, such as plant biomass, for mass production of commodity chemicals and liquid fuels to meet our ever- increasing demands Encourages sustainable green technologies for the utilization of renewable resources Offers timely solutions to help address the energy problem as non-renewable fossil oil will soon be unavailable

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Автор: Jhuma Sadhukhan

As the range of feedstocks, process technologies and products expand, biorefineries will become increasingly complex manufacturing systems. Biorefineries and Chemical Processes: Design, Integration and Sustainability Analysis presents process modelling and integration, and whole system life cycle analysis tools for the synthesis, design, operation and sustainable development of biorefinery and chemical processes. Topics covered include: Introduction: An introduction to the concept and development of biorefineries. Tools: Included here are the methods for detailed economic and environmental impact analyses; combined economic value and environmental impact analysis; life cycle assessment (LCA); multi-criteria analysis; heat integration and utility system design; mathematical programming based optimization and genetic algorithms. Process synthesis and design: Focuses on modern unit operations and innovative process flowsheets. Discusses thermochemical and biochemical processing of biomass, production of chemicals and polymers from biomass, and processes for carbon dioxide capture. Biorefinery systems: Presents biorefinery process synthesis using whole system analysis. Discusses bio-oil and algae biorefineries, integrated fuel cells and renewables, and heterogeneous catalytic reactors. Companion website: Four case studies, additional exercises and examples are available online, together with three supplementary chapters which address waste and emission minimization, energy storage and control systems, and the optimization and reuse of water. This textbook is designed to bridge a gap between engineering design and sustainability assessment, for advanced students and practicing process designers and engineers.

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Автор: Группа авторов

In order to successfully compete as a sustainable energy source, the value of biomass must be maximized through the production of valuable co-products in the biorefinery. Specialty chemicals and other biobased products can be extracted from biomass prior to or after the conversion process, thus increasing the overall profitability and sustainability of the biorefinery. Biorefinery Co-Products highlights various co-products that are present in biomass prior to and after processing, describes strategies for their extraction , and presents examples of bioenergy feedstocks that contain high value products. Topics covered include: Bioactive compounds from woody biomass Phytochemicals from sugar cane, citrus waste and algae Valuable products from corn and other oil seed crops Proteins from forages Enhancing the value of existing biomass processing streams Aimed at academic researchers, professionals and specialists in the bioenergy industry, Biorefinery Co-Products is an essential text for all scientists and engineers working on the efficient separation, purification and manufacture of value-added biorefinery co-products. For more information on the Wiley Series in Renewable resources, visit www.wiley.com/go/rrs

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Автор: Khalid Rehman Hakeem

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Автор: Группа авторов

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Автор: Группа авторов

Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can affect important improvements in one of the most significant – and most challenging – areas of drug discovery. • Written by world experts to provide practical solutions to increase brain penetration or minimize CNS side-effects • Reviews state-of-the-art in silico, in vitro, and in vivo tools to assess brain penetration and advanced CNS drug delivery strategies • Covers BBB physiology, medicinal chemistry design principles, free drug hypothesis for the BBB, and transport mechanisms including passive diffusion, uptake/efflux transporters, and receptor-mediated processes • Highlights the advances in modelling BBB pharmacokinetics and dynamics relationships (PK/PD) and physiologically-based pharmacokinetics (PBPK) • Discusses case studies of successful CNS and non-CNS drugs, lessons learned and paths to the market

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Автор: Группа авторов

Brain–computer interfaces (BCI) are devices which measure brain activity and translate it into messages or commands, thereby opening up many investigation and application possibilities. This book provides keys for understanding and designing these multi-disciplinary interfaces, which require many fields of expertise such as neuroscience, statistics, informatics and psychology. This first volume, Methods and Perspectives, presents all the basic knowledge underlying the working principles of BCI. It opens with the anatomical and physiological organization of the brain, followed by the brain activity involved in BCI, and following with information extraction, which involves signal processing and machine learning methods. BCI usage is then described, from the angle of human learning and human-machine interfaces. The basic notions developed in this reference book are intended to be accessible to all readers interested in BCI, whatever their background. More advanced material is also offered, for readers who want to expand their knowledge in disciplinary fields underlying BCI. This first volume will be followed by a second volume, entitled Technology and Applications

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Автор: Helene Panzarino

Get the business funding you need to secure your success The issue of funding is one of the biggest pain points for small- and medium-sized businesses—and one that comes up on a daily basis. Whether you're unsure about how to go about getting a loan, unfamiliar with the different options available to you or confused as to which would be the right solution for your particular business, Business Funding For Dummies provides plain-English, down-to-earth guidance on everything you need to successfully fund your business venture. Friendly, authoritative, and with a dash of humor thrown in for fun, this hands-on guide takes the fear out of funding and walks you step-by-step through the process of ensuring your business is financially viable. From crowd funding and angels to grants and friends, families, and fools, it covers every form of funding available—and helps you hone in on and secure the ones that are right for your unique needs. Includes mini case studies, quotes, and plenty of examples Offers excerpts from interviews with financiers and entrepreneurs Topics covered include all forms of funding Covers angels in the UK and abroad If you're the owner or director of a small-to-medium-sized business looking to start an SME, but have been barking up the wrong tree, Business Funding For Dummies is the fast and easy way to get the funds you need.

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Автор: Paul Tiffany

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Автор: Tobias Amely

"BWL f?r Dummies" ist eine kompetente und umfassende Einf?hrung in die Betriebswirtschaftslehre. Dabei stellen die Autoren die wesentlichen Elemente und Grundbegriffe der Betriebswirtschaftslehre vor und zeigen die Bez?ge zur Unternehmenspraxis auf. Folgende Themen werden behandelt: Materialwirtschaft, Leistungsbereitstellung und Produktion, Marketing, Investition und Finanzierung, Unternehmensorganisation und -f?hrung, Rechnungswesen, Controlling.

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Автор: Группа авторов

Provides, in one handbook, comprehensive coverage of one of the hottest topics in stereoselective chemistry Written by leading international authors in the field, this book introduces readers to C-H activation in asymmetric synthesis along with all of its facets. It presents stereoselective C-H functionalization with a broad coverage, from outer-sphere to inner-sphere C-H bond activation, and from the control of olefin geometry to the induction of point, planar and axial chirality. Moreover, methods wherein asymmetry is introduced either during the C-H activation or in a different elementary step are discussed. Presented in two parts?asymmetric activation of C(sp3)-H bonds and stereoselective synthesis implying activation of C(sp2)-H bonds?CH-Activation for Asymmetric Synthesis showcases the diversity of stereogenic elements, which can now be constructed by C-H activation methods. Chapters in Part 1 cover: C(sp3)-H bond insertion by metal carbenoids and nitrenoids; stereoselective C-C bond and C-N bond forming reactions through C(sp3)?H bond insertion of metal nitrenoids; enantioselective intra- and intermolecular couplings; and more. Part 2 looks at: C-H activation involved in stereodiscriminant step; planar chirality; diastereoselective formation of alkenes through C(sp2)?H bond activation; amongst other methods. -Covers one of the most rapidly developing fields in organic synthesis and catalysis -Clearly structured in two parts (activation of sp3- and activation of sp2-H bonds) -Edited by two leading experts in C-H activation in asymmetric synthesis CH-Activation for Asymmetric Synthesis will be of high interest to chemists in academia, as well as those in the pharmaceutical and agrochemical industry.

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Автор: Stefan Mathias Sarge

Clearly divided into three parts, this practical book begins by dealing with all fundamental aspects of calorimetry. The second part looks at the equipment used and new developments. The third and final section provides measurement guidelines in order to obtain the best results. The result is optimized knowledge for users of this technique, supplemented with practical tips and tricks.

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Автор: Gerhardus de Jong

This monograph offers the reader a complete overview on both principles and applications of CE-MS. Starting with an introductory chapter on detection in CE, also related and more specialized techniques such as electrophoretic and chromatographic preconcentration are discussed. A special emphasis is put on CE-MS interfaces, which are described in detail. In a separate chapter, attention is paid to sheath-liquid interfacing. The developments and possibilities of microchip CE-MS are also described. Applications to all relevant areas are discussed in distinct chapters, each written by experts in the respective fields. Besides applications in pharmaceutical analysis and bioanalysis, recent implementations in food science, forensic analysis, analysis of intact proteins, metabolomics and proteomics are highlighted. MS is a perfectly appropriate detection system for CE, as efficient separation is coupled to sensitive and selection detection. Moreover, MS can provide structure information on the separated compounds. CE-MS has now been developed into a strong hyphenated system complementary to LC-MS. This monograph is an unique source of knowledge for everyone dealing with and interested in CE-MS.

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Автор: Группа авторов

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Автор: Группа авторов

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Автор: Группа авторов

This ready reference presents environmentally friendly and stereoselective methods of modern biocatalysis. The experienced and renowned team of editors have gathered top international authors for this book. They cover such emerging topics as chemoenzymatic methods and multistep enzymatic reactions, while showing how these novel methods and concepts can be used for practical applications. Multidisciplinary topics, including directed evolution, dynamic kinetic resolution, and continuous-flow methodology are also discussed. From the contents: * Directed Evolution of Ligninolytic Oxidoreductases: from Functional Expression to Stabilization and Beyond * New Trends in the In Situ Enzymatic Recycling of NAD(P)(H) Cofactors * Monooxygenase-Catalyzed Redox Cascade Biotransformations * Biocatalytic Redox Cascades Involving w-Transaminases * Multi-Enzyme Systems and Cascade Reactions Involving Cytochrome P450 Monooxygenases * Chemo-Enzymatic Cascade Reactions for the Synthesis of Glycoconjugates * Synergies of Chemistry and Biochemistry for the Production of Beta-Amino Acids * Racemizable Acyl Donors for Enzymatic Dynamic Kinetic Resolution * Stereoselective Hydrolase-Catalyzed Processes in Continuous-Flow Mode * Perspectives on Multienzyme Process Technology * Nitrile Converting Enzymes Involved in Natural and Synthetic Cascade Reactions * Mining Genomes for Nitrilases * Key-Study on the Kinetic Aspects of the In-Situ NHase/AMase Cascade System of M. imperiale Resting Cells for Nitrile Bioconversion * Enzymatic Stereoselective Synthesis of Beta-Amino Acids * New Applications of Transketolase: Cascade Reactions for Assay Development * Aldolases as Catalyst for the Synthesis of Carbohydrates and Analogs * Enzymatic Generation of Sialoconjugate Diversity * Methyltransferases in Biocatalysis * Chemoenzymatic Multistep One-Pot Processes

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Автор: Nadean H. Tanner

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Автор: Stephen R. Bolsover

An accessible and straightforward intro to cell biology In the newly revised Fourth Edition of Cell Biology: A Short Course , a distinguished team of researchers delivers a concise and accessible introduction to modern cell biology, integrating knowledge from genetics, molecular biology, biochemistry, physiology, and microscopy. The book places a strong emphasis on drawing connections between basic science and medicine. Telling the story of cells as the units of life in a colorful and student-friendly manner, Cell Biology: A Short Course takes an “essentials only” approach. It conveys critical points without overburdening the reader with extraneous or secondary information. Clear diagrams and examples from current research accompany special boxed sections that focus on the importance of cell biology in medicine and industry. A new feature, “BrainBoxes” describes some of the key people who created the current understanding of Cell Biology. The book has been thoroughly revised and updated since the last edition and includes: Thorough introduction to cells and tissues, membranes, organelles, and the structure of DNA and genetic code Explorations of DNA as a data storage medium, transcription and the control of gene expression, and recombinant DNA and genetic engineering Discussion of the manufacture of proteins, protein structure, and intracellular protein trafficking Description of ions and voltages, intracellular and extracellular signaling Introduction to the cytoskeleton and cell movement Discussion of cell division and apoptosisPerfect for undergraduate students seeking an accessible, one-stop reference on cell biology, Cell Biology: A Short Course is also an ideal reference for pre-med students.

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Автор: Группа авторов

Offers a comprehensive overview of cell culture engineering, providing insight into cell engineering, systems biology approaches and processing technology In Cell Culture Engineering: Recombinant Protein Production, editors Gyun Min Lee and Helene Faustrup Kildegaard assemble top class authors to present expert coverage of topics such as: cell line development for therapeutic protein production; development of a transient gene expression upstream platform; and CHO synthetic biology. They provide readers with everything they need to know about enhancing product and bioprocess attributes using genome-scale models of CHO metabolism; omics data and mammalian systems biotechnology; perfusion culture; and much more. This all-new, up-to-date reference covers all of the important aspects of cell culture engineering, including cell engineering, system biology approaches, and processing technology. It describes the challenges in cell line development and cell engineering, e. g. via gene editing tools like CRISPR/Cas9 and with the aim to engineer glycosylation patterns. Furthermore, it gives an overview about synthetic biology approaches applied to cell culture engineering and elaborates the use of CHO cells as common cell line for protein production. In addition, the book discusses the most important aspects of production processes, including cell culture media, batch, fed-batch, and perfusion processes as well as process analytical technology, quality by design, and scale down models. -Covers key elements of cell culture engineering applied to the production of recombinant proteins for therapeutic use -Focuses on mammalian and animal cells to help highlight synthetic and systems biology approaches to cell culture engineering, exemplified by the widely used CHO cell line -Part of the renowned «Advanced Biotechnology» book series Cell Culture Engineering: Recombinant Protein Production will appeal to biotechnologists, bioengineers, life scientists, chemical engineers, and PhD students in the life sciences.

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Автор: Tanja Wuestenberg

Cellulose and its derivatives can be found in many forms in nature and is a valuable material for all manner of applications in industry. This book is authored by an expert with many years of experience as an application engineer at renowned cellulose processing companies in the food industry. All the conventional and latest knowledge available on cellulose and its derivatives is presented. The necessary details are elucidated from a theoretical and practical viewpoint, while retaining the focus on food applications. This book is an essential source of information and includes recommendations and instructions of a general nature to assist readers in the exploration of possible applications of cellulose and its derivatives, as well as providing food for thought for the generation of new ideas for product development. Topics include gelling and rheological properties, synergistic effects with other hydrocolloids, as well as nutritional and legal aspects. The resulting compilation covers all the information and advice needed for the successful development, implementation, and handling of cellulose-containing products.

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Автор: Wadood Y. Hamad

Research into cellulose nanocrystals is currently in an exponential growth phase, with research into potential applications now strengthened by recent advances in nanomanufacturing. The possibility of routine commercial production of these advanced materials is now becoming a reality. Cellulose Nanocrystals: Properties, Production and Applications provides an in-depth overview of the materials science, chemistry and physics of cellulose nanocrystals, and the technical development of advanced materials based on cellulose nanocrystals for industrial and medical applications. Topics covered include: • A comprehensive treatment of the structure, morphology and synthesis of cellulose nanocrystals. • The science and engineering of producing cellulose nanocrystals and the challenges involved in nanomanufacturing on a large industrial scale. • Surface/interface modifications of cellulose nanocrystals for the development of novel biomaterials with attractive structural and functional properties. • The scientific bases for developing cellulose-based nanomaterials with advanced functionalities for industrial/medical applications and consumer products. • Discussions on the (i) reinforcing potential of cellulose nanocrystals in polymer nanocomposites, (ii) utilization of these nanocrystals as efficient templates for developing tunable photonic materials, as well as (iii) applications in sustainable electronics and biomedicine. Cellulose Nanocrystals: Properties, Production and Applications will appeal to audiences in the physical, chemical and biological sciences as well as engineering disciplines. It will be of critical interest to industrialists seeking to develop sustainable new materials for the advanced industrial economies of the 21st century, ranging from adaptive “smart” packaging materials, to new chiral, mesoporous materials for optoelectronics and photonics , to high-performance nanocomposites for structural applications.

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Автор: Группа авторов

Cellulosic Energy Cropping Systems presents a comprehensive overview of how cellulosic energy crops can be sustainably produced and converted to affordable energy through liquid fuels, heat and electricity. The book begins with an introduction to cellulosic feedstocks, discussing their potential as a large-scale sustainable energy source, and technologies for the production of liquid fuels, heat and electricity. Subsequent chapters examine miscanthus, switchgrass, sugarcane and energy cane, sorghums and crop residues, reviewing their phylogeny, cultural practices, and opportunities for genetic improvement. This is followed by a detailed focus on woody crops, including eucalyptus, pine, poplar and willow. Critical logistical issues associated with both herbaceous and woody feedstocks are reviewed, and alternate strategies for harvesting, transporting, and storing cellulosic materials are also examined. The final sectionof the booktackles the challenge of achieving long-term sustainability, addressing economic, environmental and social factors. Cellulosic Energy Cropping Systems is a valuable resource for academics, students and industry professionals working in the field of biomass cultivation and conversion, bioenergy, crop science and agriculture. Topics covered include: Identifying suitable cellulosic energy crops that are adapted to a wide range of climates and soils Best management practices for sustainably growing, harvesting, storing, transporting and pre-processing these crops The development of integrated cellulosic energy cropping systems for supplying commercial processing plants Challenges and opportunities for the long-term sustainability of cellulosic energy crops This book was conceived and initiated by David I. Bransby, Professor of Energy and Forage Crops in the Department of Crop, Soil and Environmental Sciences at Auburn University, USA. For more information on the Wiley Series in Renewable Resources, visit www.wiley.com/go/rrs

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