зарубежная образовательная литература (страница 92)

Автор: Volker Munch

Patentrecht, Markenrecht und Designschutz bilden einen Bereich, der standigem Wandel unterworfen ist. Selbst fur Spezialisten ist es zur Herausforderung geworden, Rechte und Forschungsergebnisse zu schutzen in einem internationalen Umfeld, das taglich komplexer wird. Basierend auf dem 1991 erschienenen erfolgreichen Werk «Patentbegriffe von A bis Z» und erganzt um ein dreisprachiges Fachwortverzeichnis, fuhrt das hoch vernetzte Glossar durch den Dschungel der Begrifflichkeiten und berucksichtigt dabei alle aktuellen rechtlichen Anderungen wie: – einheitliche Marken fur die EU – Auswirkung von EU-Richtlinien auf nationale Patentsysteme – EPU ab Dezember 2007 – weltweite Harmonisierung des gewerblichen Rechtsschutzes (TRIPS-Abkommen) inklusive Asien unter besonderer Berucksichtigung Japans – Anderung des US-Patentrechts – Gemeinsamkeiten und Unterschiede des Rechts in verschiedenen Landern Mit eingangigen Beispielen und kompetenten Erklarungen werden Begriffe erlautert, mit denen Erfinder und Patentanmelder am haufigsten konfrontiert werden. Tabellen und Formulare im Anhang geben dem Leser einen Uberblick uber den typischen Lebenslauf einer Anmeldung und helfen ihm, das Zahlen- und Begriffswerk auf den Deckblattern von Patentschriften zu verstehen. Den Umgang mit den entscheidenden Begriffen im nationalen und internationalen Umfeld klart ein Verzeichnis von Fachbegriffen in deutscher, englischer und franzosischer Sprache. Ein absolutes Muss beim Studium der internationalen Literatur – fur Wissenschaftler, Erfinder, Patentanwalte, Dokumentations- und Recherchespezialisten, Ubersetzer, Dolmetscher sowie Studenten und Berufsanfanger auf dem Gebiet des gewerblichen Rechtsschutzes. Mit diesem Buch werden sich Erfinder leicht tun, ihr Patent anzumelden. Kunststoffe Das Buch ist sicher nicht nur Spezialisten zu empfehlen – gerade Studenten und Berufsanfangern durfte es eine gro?e Hilfe sein. Kunststoff-Journal Eine wesentliche Hilfestellung fur potentielle Patentanmelder, was das Werk uber ein reines Worterbuch hinaushebt und tatsachlich sowohl fur Ubersetzer und Dokumentalisten als auch fur Fachleute ein unentbehrliches Hilfsmittel darstellt. TermNet – Jornal of the International Network for Terminology

Купить

Автор: John Buchaca

Useful tips and step-by-step guidance from filing to issue to license Acquire and protect your share of this major business asset Want to secure and exploit the intellectual property rights due you or your company? This easy-to-follow guide shows you how – helping you to evaluate your idea's commercial potential, conduct patent and trademark searches, document the invention process, license your IP rights, and comply with international laws. Plus, you get detailed examples of each patent application type! Discover how to: Avoid application blunders Register trademarks and copyrights Meet patent requirements Navigate complex legal issues Protect your rights abroad The entire body of U.S. patent laws Example office actions and amendments Sample forms Trademark registration certificates Application worksheets See the CD appendix for details and complete system requirements. Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.

Купить

Автор: Гилберт Кит Честертон

Eine Dame meldet sich nicht mehr. Pater Brown reist auf Bitten seiner Nachbarin nach Cornwall, wo die Vermisste in einem Sanatorium gearbeitet hat. Mit Hilfe der jungen Lucy Paxton startet er seine Recherchen und macht kurz darauf eine grausige Entdeckung. Ab diesem Zeitpunkt scheint niemand in dem Sanatorium hoch ?ber Manderley Cove mehr sicher zu sein. Die Legende der schwarzen Nonne ist pl?tzlich wieder in aller Munde, und tats?chlich wird die geisterhafte Erscheinung gleich von mehreren Personen gesehen. Doch Pater Brown glaubt nicht an Gespenster. Er setzt alles daran, die unheimliche Gestalt zu stellen und die alles entscheidende Frage zu kl?ren: welcher gerissene M?rder h?lt sich hinter der schwarzen Maskierung verborgen?

Исполнители: Douglas Welbat

Купить

Автор: Jamie Goode A

This book brings together contributions from key investigators in the area of pathological pain. It covers the molecular basis of receptors and channels involved in nociception, the possible messages that cause neuropathic plasticity, spinal plasticity in neuropathy, plastic changes in opioid systems in neuropathy and opioid tolerance, and plastic changes related to pathological pain.

Купить

Автор: McDonald Jeanette

The contributors to this volume are academics working directly or indirectly with teaching and learning centers and professional communities, serving in the capacity of educational developer, researcher, or specialist; unit manager or director; or senior administrator. Drawing on survey and interview data, individual experience or perspective, and familiarity with the educational literature, they offer a context to understand and appreciate how the field of educational development, developer practice, and individual pathways have evolved, further highlighting what territory remains to be explored and uncovered. Over the last fifty years, educational development has evolved from an informal set of instructional improvement activities championed by individuals to a scholarly field of study and practice that aims to advance teaching and learning at the individual, institutional and (more recently) sector levels. During this time, educational development work has moved from the fringes to the mainstream of the higher education landscape, bringing to the community a diverse group of dedicated academic professionals. This volume draws on their experience and insight to provide an invaluable guide to future challenges and issues. This is the 122nd volume of the Jossey-Bass higher education quarterly report series New Directions for Teaching and Learning, which offers a comprehensive range of ideas and techniques for improving college teaching based on the experience of seasoned instructors and the latest findings of educational and psychological researchers.

Купить

Автор: Frank Buschmann

The eagerly awaited Pattern-Oriented Software Architecture (POSA) Volume 4 is about a pattern language for distributed computing. The authors will guide you through the best practices and introduce you to key areas of building distributed software systems. POSA 4 connects many stand-alone patterns, pattern collections and pattern languages from the existing body of literature found in the POSA series. Such patterns relate to and are useful for distributed computing to a single language. The panel of experts provides you with a consistent and coherent holistic view on the craft of building distributed systems. Includes a foreword by Martin Fowler A must read for practitioners who want practical advice to develop a comprehensive language integrating patterns from key literature.

Купить

Автор: Jeff Strong

Here's how to make sound decisions about a desktop studio Get the lowdown on equipment, design your studio space, and set your music free! If you've been dreaming of making music with your computer, wake up and get started! Musician Jeff Strong clears a path for you through all the confusing options, helping you sort out hardware and software choices, coax the sound you want from your equipment, work with equalizers and processors, and start your creative juices flowing! Discover how to * Choose the right system and install software * Optimize studio sound for recording and mixing * Understand audio interfaces, sound cards, and MIDI gear * Compare popular programs * Mix and master your tracks

Купить

Автор: Diane Koers

Not feeling too peachy about computerizing your accounting system? Relax! Peachtree For Dummies, 3rd Edition will show you how to set up your company in Peachtree and then use it to pay bills, invoice customers, pay employees, produce financial reports, and more. You’ll quickly discover how Peachtree can save you time, effort, and money so that you no longer have to do your accounting by hand or pay someone else to do it for you. Publishing to coincide with the latest release of Peachtree, this third edition is revised to cover the newest updates and enhancements made to the most recent version of Peachtree. Veteran authors Elaine Marmel and Diane Koers break down the capabilities of Peachtree Premium Accounting, from building an effective chart of accounts, to customizing forms and modifying reports, to setting up default information that will save you time down the line. You’ll also discover how to: Work with purchase orders Sell products and services Generate invoices Track project costs Produce income statements Back up and restore data Balance accounts Manage inventory Handle customer prepayments Pay for purchase orders with a credit card Keep your account information safe Packed with examples of everyday, real-life situations, Peachtree For Dummies, 3rd Edition is the reference you need so that you can put Peachtree to work for you and get the job done quickly and correctly.

Купить

Автор: Лизель Полински

Опора на двигательную и познавательную активность младенца в первый год его жизни – ключевое положение Пражской программы «Родители и дети» (PEKiP), которая с середины 70-х годов XX века широко распространилась и по сей день успешно применяется в разных странах. Первое издание книги «PEKiP: игра и движение» появилось в 1993 г. и стало бестселлером в Германии. В книге, иллюстрированной многочисленными фотографиями, представлены двигательные и сенсорные игры, которые способствуют гармоничному развитию младенца. Описываемый в ней подход поможет родителям лучше понимать своего ребенка, преодолевать возникающие трудности, сделает отношения между ними более близкими и теплыми. Для родителей детей первого года жизни, а также педиатров, психологов и других специалистов, причастных к работе с детьми раннего возраста.

Купить

Автор: Hugh Jenkyns C

This first IAS Special Publication contains the oral presentations from a special symposium on pelagic sediments held in Zurich in 1973. The aim of the symposium was to bring together sea-borne researchers involved with the Deep Sea Drilling Project and land-locked researchers studying ancient sediments. If you are a member of the International Association of Sedimentologists, for purchasing details, please see: http://www.iasnet.org/publications/details.asp?code=SP1

Купить

Автор: Группа авторов

Peptides serve as effective drugs in the clinic today. However the inherent drawbacks of peptide structures can limit their efficacy as drugs. To overcome this researchers are developing new methods to create ‘tailor-made’ peptides and proteins with improved pharmacological properties. Design of Peptides and Proteins provides an overview of the experimental and computational methods for peptide and protein design, with an emphasis on specific applications for therapeutics and biomedical research. Topics covered include: Computer modeling of peptides and proteins Peptidomimetics Design and synthesis of cyclic peptides Carbohydrates in peptide and protein design De novo design of peptides and proteins Medical development applications An extended case study – the design of insulin variants Design of Peptides and Proteins presents the state-of-the-art of this exciting approach for therapeutics, with contributions from international experts. It is an essential resource for academic and industrial scientists in the fields of peptide and protein drug design, biomedicine, biochemistry, biophysics, molecular modelling, synthetic organic chemistry and medicinal/pharmaceutical chemistry.

Купить

Автор: Hans-Dieter Jakubke

This mini-encyclopedia contains more than 1,500 alphabetical entries from the entire field of peptide science in one handy volume, as well as the technical terms, acronyms and concepts used in peptide chemistry. It also features the complete sequence of more than 800 peptides, numerous illustrations and numerous cross-references. Areas covered include: – biological peptides and small proteins – peptide hormones – pharmaceutical peptides – peptide antibiotics – peptide inhibitors – peptide reagents – peptide tags – structural classes – synthesis and purification – analytical methods – proteomics and peptidomics. Condensed yet accessible, only essential information is displayed, extensively linked via references to the recent scientific literature for further study.

Купить

Автор: CIBA Foundation Symposium

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Купить

Автор: Matthew Diamond

Seemingly simple behaviours turn out, on reflection, to be discouragingly complex. For many years, cognitive operations such as sensation, perception, comparing percepts to stored models (short-term and long-term memory), decision-making and planning of actions were treated by most neuroscientists as separate areas of research. This was not because the neuroscience community believed these operations to act independently—it is intuitive that any common cognitive process seamlessly interweaves these operations—but because too little was known about the individual processes constituting the full behaviour, and experimental paradigms and data collection methods were not sufficiently well developed to put the processes in sequence in any controlled manner. These limitations are now being overcome in the leading cognitive neuroscience laboratories, and this book is a timely summary of the current state of the art. The theme of the book is how the brain uses sensory information to develop and decide upon the appropriate action, and how the brain determines the appropriate action to optimize the collection of new sensory information. It addresses several key questions. How are percepts built up in the cortex and how are judgments of the percept made? In what way does information flow within and between cortical regions, and what is accomplished by successive (and reverberating) stages of processing? How are decisions made about the percept subsequently acted upon, through their conversion to a response according to the learned criterion for action? How does the predicted or expected sensation interact with the actual incoming flow of sensory signals? The chapters and discussions in the book reveal how answering these questions requires an understanding of sensory–motor loops: our perception of the world drives new actions, and the actions undertaken at any moment lead to a new ‘view’ of the world. This book is a fascinating read for all clinical and experimental psychologists and neuroscientists, as well as anyone interested in how we perceive the world and act within it.

Купить

Автор: Wu Dongrui

Explains for the first time how «computing with words» can aid in making subjective judgments Lotfi Zadeh, the father of fuzzy logic, coined the phrase «computing with words» (CWW) to describe a methodology in which the objects of computation are words and propositions drawn from a natural language. Perceptual Computing explains how to implement CWW to aid in the important area of making subjective judgments, using a methodology that leads to an interactive device—a «Perceptual Computer»—that propagates random and linguistic uncertainties into the subjective judgment in a way that can be modeled and observed by the judgment maker. This book focuses on the three components of a Perceptual Computer—encoder, CWW engines, and decoder—and then provides detailed applications for each. It uses interval type-2 fuzzy sets (IT2 FSs) and fuzzy logic as the mathematical vehicle for perceptual computing, because such fuzzy sets can model first-order linguistic uncertainties whereas the usual kind of fuzzy sets cannot. Drawing upon the work on subjective judgments that Jerry Mendel and his students completed over the past decade, Perceptual Computing shows readers how to: Map word-data with its inherent uncertainties into an IT2 FS that captures these uncertainties Use uncertainty measures to quantify linguistic uncertainties Compare IT2 FSs by using similarity and rank Compute the subsethood of one IT2 FS in another such set Aggregate disparate data, ranging from numbers to uniformly weighted intervals to nonuniformly weighted intervals to words Aggregate multiple-fired IF-THEN rules so that the integrity of word IT2 FS models is preserved Free MATLAB-based software is also available online so readers can apply the methodology of perceptual computing immediately, and even try to improve upon it. Perceptual Computing is an important go-to for researchers and students in the fields of artificial intelligence and fuzzy logic, as well as for operations researchers, decision makers, psychologists, computer scientists, and computational intelligence experts.

Купить

Автор: Hugo S. L. Hens

Just like building physics, performance based building design was hardly an issue before the energy crises of the 1970s. With the need to upgrade energy efficiency, the interest in overall building performance grew. The term «performance» encompasses all building-related physical properties and qualities that are predictable during the design stage and controllable during and after construction. The term «predictable» demands calculation tools and physical models that allow evaluating a design, whereas «controllable» presumes the existence of measuring methods available on site. The basis for a system of performance arrays are the functional demands, the needs for accessibility, safety, well-being, durability, energy efficiency and sustainability and the requirements imposed by the usage of a building. As the first of two volumes, this book applies the performance rationale, advanced in applied building physics, to the design and construction of buildings. After an overview of materials for thermal insulation, water proofing, air tightening and vapour tightening and a discussion on joints, building construction is analysed, starting with the excavations. Then foundations, below and on grade constructions, typical load bearing systems and floors pass the review to end with massive outer walls insulated at the inside and the outside and cavity walls. Most chapters build on a same scheme: overview, overall performance evaluation, design and construction. The book is absolutely recommended to undergraduates and graduates in architectural and building engineering, though also building engineers, who want to refresh their knowledge, may benefit. The level of discussion assumes the reader has a sound knowledge of building physics, along with a background in structural engineering, building materials and building construction. Where and when needed, input and literature from over the world was used, reason why each chapter ends listing references and literature.

Купить

Автор: Hugo S. L. Hens

Just like building physics, performance based building design was hardly an issue before the energy crises of the 1970ies. With the need to upgrade energy efficiency, the interest in overall building performance grew. The term «performance» encompasses all building-related physical properties and qualities that are predictable during the design stage and controllable during and after construction. The term «predictable» demands calculation tools and physical models that allow evaluating a design, whereas «controllable» presumes the existence of measuring methods available on site. The basis for a system of performance arrays are the functional demands, the needs for accessibility, safety, well-being, durability, energy efficiency and sustainability and the requirements imposed by the usage of a building. In continuation of Vol. 1 this second volume discusses light-weight construction with wooden and metal elements, roofing systems, facades, and ends with finishes and the overall risk analysis. Most chapters build on a same scheme: overview, overall performance evaluation, design and construction. The work is absolutely recommended to undergraduates and graduates in architectural and building engineering, though also building engineers, who want to refresh their knowledge, may benefit. The level of discussion assumes the reader has a sound knowledge of building physics, along with a background in structural engineering, building materials and building construction. Where and when needed, input and literature from over the world was used, reason why each chapter ends listing references and literature.

Купить

Автор: Gladeana McMahon

Performance coaching is a modern and rapidly growing method used to assist development, and involves helping individuals to improve their performance in all areas of their life, with a particular emphasis on the workplace. Performance coaching draws parallels with NLP and often focuses on the psychology of excellence – making what’s good even better, and helping individuals keep ahead of the game. On an organisational level it can include helping managers to consider how to get the best from their staff, peers and superiors, as well as helping to identify strengths, weaknesses, opportunities and threats. A performance coach assists individuals in building on their successes and helps to design, plan and instigate successful business/life strategies. Despite its popularity confusion still surrounds coaching. It is a relatively new area and there is still a lack of understanding about how best to use coaching and in what specific situations it will be most effective. In addition to this, anyone can assume a performance/professional/business/life coach title without holding any particular qualification or registration. With this increased awareness and confusion the need for a no-nonsense book on the topic that offers trusted advice is needed all the more, which is where Performance Coaching For Dummies steps in.

Купить

Автор: William J. Rothwell

Praise for Performance Consulting «You hold in your hands an outstanding portrayal of the half-century evolution of performance improvement. Rothwell and his colleagues have written the most comprehensive performance consulting book on the market. From data collection and analysis to implementing solutions, Performance Consulting provides a roadmap to guide you on the path to becoming a successful performance consultant. The roadmap includes countless signposts in the form of exercises, processes, examples, tools, and advice to ensure you reach your final destination successfully.» —Elaine Biech, president, ebb associates and author of The Business of Consulting «This book provides a wealth of resources performance consultants can use for performance analysis and solution selection. The many case studies, references, and discussion questions throughout the text make this book both practical and substantive.» —Dana and Jim Robinson, co-authors of Performance Consulting: A Practical Guide for HR and Learning Professionals «In today's economic realities, performance consulting and performance improvement are critical to organizational success. The challenge for human resource development professionals is to shift the focus to performance improvement, not just applying classic training and learning solutions. Rothwell and his team have assembled perhaps the most comprehensive reference on this important field, complete with examples, illustrations, and a description of all of the pertinent models. This will be a 'must have' reference for any person involved in human resource development and human capital development.» —Jack Phillips Ph.D., chairman, ROI Institute, author of The Value of Learning

Купить

Автор: Nielsen Steffen Bohni

This issue focuses on connections between performance management and evaluation, a contentious topic at the moment. It does so by placing evaluation and monitoring under the overarching concept of performance management, and then by investigating five complementarities between performance monitoring and measurement on the one hand, and evaluation on the other. These complementarities are: Sequential Informational Organizational Methodical Hierarchical. Several case studies discuss the uses and complementarities of evaluation and performance management in contexts including national and local governments and the work of government, philanthropic foundations, and a direct-service nonprofit agency. These cases illustrate the advantages and pitfalls in utilizing evaluative approaches within the context of performance management. This is the 137th volume of the Jossey-Bass quarterly report series New Directions for Evaluation, an official publication of the American Evaluation Association.

Купить

Автор: William Mark D

A mathematically rigorous explanation of how manufacturing deviations and damage on the working surfaces of gear teeth cause transmission-error contributions to vibration excitations Some gear-tooth working-surface manufacturing deviations of significant amplitude cause negligible vibration excitation and noise, yet others of minuscule amplitude are a source of significant vibration excitation and noise. Presently available computer-numerically-controlled dedicated gear metrology equipment can measure such error patterns on a gear in a few hours in sufficient detail to enable accurate computation and diagnosis of the resultant transmission-error vibration excitation. How to efficiently measure such working-surface deviations, compute from these measurements the resultant transmission-error vibration excitation, and diagnose the manufacturing source of the deviations, is the subject of this book. Use of the technology in this book will allow quality spot checks to be made on gears being manufactured in a production run, to avoid undesirable vibration or noise excitation by the manufactured gears. Furthermore, those working in academia and industry needing a full mathematical understanding of the relationships between tooth working-surface deviations and the vibration excitations caused by these deviations will find the book indispensable for applications pertaining to both gear-quality and gear-health monitoring. Key features: Provides a very efficient method for measuring parallel-axis helical or spur gears in sufficient detail to enable accurate computation of transmission-error contributions from working-surface deviations, and algorithms required to carry out these computations, including examples Provides algorithms for computing the working-surface deviations causing any user-identified tone, such as ‘ghost tones,’ or ‘sidebands’ of the tooth-meshing harmonics, enabling diagnosis of their manufacturing causes, including examples Provides explanations of all harmonics observed in gear-caused vibration and noise spectra. Enables generation of three-dimensional displays and detailed numerical descriptions of all measured and computed working-surface deviations, including examples

Купить

Автор: Ruey-Bing Hwang (Raybeam)

Provides readers an understanding of the basic physics underlying meta-materials, providing a powerful tool for analyzing their electromagnetic properties Periodic Structures: Mode-Matching Approach and Applications in Electromagnetic Engineering presents the scattering and guiding characteristics of periodic structures using the mode-matching approach and their applications in electromagnetic engineering. The book is structured so that the first three chapters provide an introduction and prepare the reader for chapters 4 to 6, which expand the formulations to electromagnetic and optical structures applicable to practical device applications. The last chapters cover very recent research topics in electromagnetics and optics. Provides an analytic approach to describing the operation of photonic crystals and related periodic structures Covers guided and leaky mode propagation in periodic surroundings, from fundamentals to practical device applications Demostrates formulation of the periodic system and applications to practical electromagnetic / optical devices, even further to metamaterials Introduces the evolution of periodic structures and their applications in microwave, millimeter wave and THz. Written by a high-impact author in electromagnetics and optics Contains mathematical derivations which can be applied directly to MATLAB programs Ideal for Graduate students and advanced undergraduates in electronic engineering, optics, physics, and applied physics, or researchers working with periodic structures

Купить

Автор: CIBA Foundation Symposium

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Купить

Автор: Группа авторов

Persistent Organic Pollutants (POPs) are toxic, resistant to degradation, bioaccumulative, and display wide spatial distribution. They accumulate in humans and wildlife, and have been linked to cancer, as well as reproductive and immunological disorders. In 2001 a global treaty on POPs was agreed, to minimise and ultimately eliminate the release of POPs into the environment. The Stockholm Convention lists 12 groups of chemicals, and as of late 2008, a further 12 chemicals are under consideration for inclusion. This book addresses all of these chemicals, but focuses particularly on currently listed POPs that are still of major concern (e.g. polychlorinated biphenyls – PCBs), as well as new and emerging POPs that have been the subject of an explosion of scientific interest in the last decade, i.e. brominated flame retardants (BFRs) and perfluorinated chemicals (PFCs). Other chapters address the challenges posed by the presence of POPs in the developing world; how the properties of chiral POPs can provide unique insights into their environmental sources, fate and behaviour; and issues arising from the presence of POPs in urban and indoor environments. Persistent Organic Pollutants provides a much-anticipated reference source for a wide audience including academics, industrial scientists and regulators.

Купить

Автор: Xing Chen

Filling the urgent need for a professional book that specifies the applications of nanoelectrochemistry for the monitoring of persistent toxic substances, this monograph clearly describes the design concept, construction strategies and practical applications of PTS sensing interfaces based on nanoelectrochemical methods. The comprehensive and systematic information not only provides readers with the fundamentals, but also inspires them to develop PTS monitoring sensors based on functional nanostructures and nanomaterials. Of interestto chemists, electrochemistry researchers, materials researchers, environmental scientists, and companies dealing with electrochemical treatment and environment.

Купить

Автор: Группа авторов

Here, the most important classes of toxic chemicals from personal care compounds are systematically covered, from cosmetics to plastics additives to pharmaceuticals. For each substance, data on toxicity and bioaccumulation in various ecosystems are given. This first comprehensive treatment of personal care environmental toxins is rounded off by a discussion of strategies in wastewater treatment to control and remove these substances.

Купить

Автор: Aron Pinczuk

The discovery of the quantized and fractional Quantum Hall Effect phenomena is among the most important physics findings in the latter half of this century. The precise quantization of the electrical resistance involved in the quantized Hall effect phenomena has led to the new definition of the resistance standard and has metrologically affected all of science and technology. This resource consists of contributions from the top researchers in the field who present recent experimental and theoretical developments. Each chapter is self-contained and includes its own set of references guiding readers to original papers and further reading on the topic.

Купить

Автор: Ali Nayfeh H

The Wiley Classics Library consists of selected books that have become recognized classics in their respective fields. With these new unabridged and inexpensive editions, Wiley hopes to extend the life of these important works by making them available to future generations of mathematicians and scientists. Currently available in the Series: T. W. Anderson The Statistical Analysis of Time Series T. S. Arthanari & Yadolah Dodge Mathematical Programming in Statistics Emil Artin Geometric Algebra Norman T. J. Bailey The Elements of Stochastic Processes with Applications to the Natural Sciences Robert G. Bartle The Elements of Integration and Lebesgue Measure George E. P. Box & Norman R. Draper Evolutionary Operation: A Statistical Method for Process Improvement George E. P. Box & George C. Tiao Bayesian Inference in Statistical Analysis R. W. Carter Finite Groups of Lie Type: Conjugacy Classes and Complex Characters R. W. Carter Simple Groups of Lie Type William G. Cochran & Gertrude M. Cox Experimental Designs, Second Edition Richard Courant Differential and Integral Calculus, Volume I RIchard Courant Differential and Integral Calculus, Volume II Richard Courant & D. Hilbert Methods of Mathematical Physics, Volume I Richard Courant & D. Hilbert Methods of Mathematical Physics, Volume II D. R. Cox Planning of Experiments Harold S. M. Coxeter Introduction to Geometry, Second Edition Charles W. Curtis & Irving Reiner Representation Theory of Finite Groups and Associative Algebras Charles W. Curtis & Irving Reiner Methods of Representation Theory with Applications to Finite Groups and Orders, Volume I Charles W. Curtis & Irving Reiner Methods of Representation Theory with Applications to Finite Groups and Orders, Volume II Cuthbert Daniel Fitting Equations to Data: Computer Analysis of Multifactor Data, Second Edition Bruno de Finetti Theory of Probability, Volume I Bruno de Finetti Theory of Probability, Volume 2 W. Edwards Deming Sample Design in Business Research

Купить

Автор: Moshood Sanni

A comprehensive and practical guide to methods for solving complex petroleum engineering problems Petroleum engineering is guided by overarching scientific and mathematical principles, but there is sometimes a gap between theoretical knowledge and practical application. Petroleum Engineering: Principles, Calculations, and Workflows presents methods for solving a wide range of real-world petroleum engineering problems. Each chapter deals with a specific issue, and includes formulae that help explain primary principles of the problem before providing an easy to follow, practical application. Volume highlights include: A robust, integrated approach to solving inverse problems In-depth exploration of workflows with model and parameter validation Simple approaches to solving complex mathematical problems Complex calculations that can be easily implemented with simple methods Overview of key approaches required for software and application development Formulae and model guidance for diagnosis, initial modeling of parameters, and simulation and regression Petroleum Engineering: Principles, Calculations, and Workflows is a valuable and practical resource to a wide community of geoscientists, earth scientists, exploration geologists, and engineers. This accessible guide is also well-suited for graduate and postgraduate students, consultants, software developers, and professionals as an authoritative reference for day-to-day petroleum engineering problem solving.

Купить

Автор: Группа авторов

Pharmaceuticals and personal care products—we can't live without them. Can the environment survive with them? Pharmaceutical and personal care products (PPCPs) are increasingly being recognized as micropollutants. In this context, pharmaceutical products encompass a diverse range of drugs used to treat various illnesses, and personal care products include everyday items such as soaps, fragrances, cleaning agents, disinfectants, and similar products. Written for professionals from different backgrounds, Pharma-Ecology bridges the knowledge and language gap and critically examines the issue of PPCP micropollutants and how to best minimize their impact on the environment. Organized systematically, it: Presents a range of pharmaceutical compounds categorized by mode of action and common usage, displaying the volumes (or number of prescriptions) that are dispersed Discusses the detection of PPCPs in the environment using instrumentation and bioassay techniques, including microarrays Covers the occurrences of PPCPs in aquatic systems, sediments, soil, and aerial environments Considers the persistence and degradation of PPCPs in the environment, and links pharmacokinetics/pharmacodynamics with the kinetics of PPCPs in the environment Explores engineering and treatment techniques that could minimize the impact of PPCPs in the environment Includes numerous tables and figures that illustrate information This is an enlightening reference for engineers, toxicologists, ecologists, micro-biologists, and chemists involved in pollution and environmental analysis; policy-makers; professionals in federal and state regulatory agencies; and pharmaceutical professionals. It is also an excellent text for undergraduate and graduate students in related fields.

Купить

Автор: Michael Webb L

The use of analytical sciences in the discovery, development and manufacture of pharmaceuticals is wide-ranging. From the analysis of minute amounts of complex biological materials to the quality control of the final dosage form, the use of analytical technology covers an immense range of techniques and disciplines. This book concentrates on the analytical aspects of drug development and manufacture, focusing on the analysis of the active ingredient or drug substance. It provides those joining the industry or other areas of pharmaceutical research with a source of reference to a broad range of techniques and their applications, allowing them to choose the most appropriate analytical technique for a particular purpose. The volume is directed at analytical chemists, industrial pharmacists, organic chemists, pharmaceutical chemists and biochemists.

Купить

Автор: Gary Walsh

Pharmaceutical Biotechnology offers students taking Pharmacy and related Medical and Pharmaceutical courses a comprehensive introduction to the fast-moving area of biopharmaceuticals. With a particular focus on the subject taken from a pharmaceutical perspective, initial chapters offer a broad introduction to protein science and recombinant DNA technology- key areas that underpin the whole subject. Subsequent chapters focus upon the development, production and analysis of these substances. Finally the book moves on to explore the science, biotechnology and medical applications of specific biotech products categories. These include not only protein-based substances but also nucleic acid and cell-based products. introduces essential principles underlining modern biotechnology- recombinant DNA technology and protein science an invaluable introduction to this fast-moving subject aimed specifically at pharmacy and medical students includes specific ‘product category chapters’ focusing on the pharmaceutical, medical and therapeutic properties of numerous biopharmaceutical products. entire chapter devoted to the principles of genetic engineering and how these drugs are developed. includes numerous relevant case studies to enhance student understanding no prior knowledge of protein structure is assumed

Купить

Автор: Kayser Oliver

This second edition of a very successful book is thoroughly updated with existing chapters completely rewritten while the content has more than doubled from 16 to 36 chapters. As with the first edition, the focus is on industrial pharmaceutical research, written by a team of industry experts from around the world, while quality and safety management, drug approval and regulation, patenting issues, and biotechnology fundamentals are also covered. In addition, this new edition now not only includes biotech drug development but also the use of biopharmaceuticals in diagnostics and vaccinations. With a foreword by Robert Langer, Kenneth J Germeshausen Professor of Chemical and Biomedical Engineering at MIT and member of the National Academy of Engineering and the National Academy of Sciences.

Купить

Автор: Oliver Kayser

With its focus on industrial pharmaceutical research, written by international experts from the industry, this book fills in a gap in the existing literature. It reflects the combination of such pharmaceutical interests as drug delivery, drug targeting, quality and safety management, drug approval and regulation, patenting issues and biotechnology fundamentals. Thus it provides practitioners in pharmaceutical biotechnology with all the relevant information from the shelf. The first part offers a comprehensive survey and review of the rapidly increasing array of biopharmaceuticals derived from the molecular biological approaches now widely available. This is followed by an extra section devoted to the very critical patenting and drug regulation issues. The whole is rounded off by detailed monographs of biotechnologically developed drugs that are already on the market. With a foreword of by Robert Langer, Kenneth J Germeshausen Professor of Chemical and Biomedical Engineering at the Massachusetts Institute of Technology. In 2002, he received the Charles Stark Draper Prize, the highest recognition for an engineer. Professor Langer is member of all three national academies – the Institute of Medicine, the National Academy of Engineering, and the National Academy of Sciences: «The book attempts to provide a balanced view of the biotechnological industry and the number of experts from industry sharing their knowledge and experience with the audience gives the book an outstanding value. All contributors provide with each chapter an up-to-date review on key topics in pharmaceutical biotechnology. This work is not only a valuable tool for the industrial expert but also for all pharmacists and scientists from related areas who wish to work with biotech drugs.»

Купить

Автор: Hansen Neal

A comprehensive guide to optimizing the lifecycle management of pharmaceutical brands The mounting challenges posed by cost containment policies and the prevalence of generic alternatives make optimizing the lifecycle management (LCM) of brand drugs essential for pharmaceutical companies looking to maximize the value of their products. Demonstrating how different measures can be combined to create winning strategies, Pharmaceutical Lifecycle Management: Making the Most of Each and Every Brand explores this increasingly important field to help readers understand what they can—and must—do to get the most out of their brands. Offering a truly immersive introduction to LCM options for pharmaceuticals, the book incorporates numerous real-life case studies that demonstrate successful and failed lifecycle management initiatives, explaining the key takeaway of each example. Filled with practical information on the process of actually writing and presenting an LCM plan, as well as how to link corporate, portfolio, and individual brand strategies, the book also offers a look ahead to predict which LCM strategies will continue to be effective in the future. While the development of new drugs designed to address unmet patient needs remains the single most important goal of any pharmaceutical company, effective LCM is invaluable for getting the greatest possible value from existing brands. Pharmaceutical Lifecycle Management walks you through the process step by step, making it indispensable reading for pharmaceutical executives and managers, as well as anyone working in the fields of drug research, development, and regulation.

Купить

Автор: Shayne Cox Gad

This handbook features contributions from a team of expert authors representing the many disciplines within science, engineering, and technology that are involved in pharmaceutical manufacturing. They provide the information and tools you need to design, implement, operate, and troubleshoot a pharmaceutical manufacturing system. The editor, with more than thirty years' experience working with pharmaceutical and biotechnology companies, carefully reviewed all the chapters to ensure that each one is thorough, accurate, and clear.

Купить

Автор: Peter Harrington J

There is a need to explain that generic versions of a drug may not be manufactured by the same process as brand-name drugs and that the different processes may have dramatically different environmental impacts. Two global forces are at odds today—the push for «greener» processes and the push for lower drug prices. This book brings this conflict into sharp focus by discussing in detail the published process chemistry for top-selling small molecule drugs. Providing insights about process route selection, choice of reagents, and reaction conditions, Pharmaceutical Process Chemistry for Synthesis guides process chemists in identifying best processes for manufacturing these blockbuster drugs as they lose patent protection. Further, it highlights the strategies and methodology that might be useful for expediting the process research and development of the blockbusters of the future. Written from a refreshingly objective perspective, this book is essential for process chemists who need to devise practical syntheses for increasingly complex drugs in a constantly decreasing time frame.

Купить

Автор: Группа авторов

A practical guide to Quality by Design for pharmaceutical product development Pharmaceutical Quality by Design: A Practical Approach outlines a new and proven approach to pharmaceutical product development which is now being rolled out across the pharmaceutical industry internationally. Written by experts in the field, the text explores the QbD approach to product development. This innovative approach is based on the application of product and process understanding underpinned by a systematic methodology which can enable pharmaceutical companies to ensure that quality is built into the product. Familiarity with Quality by Design is essential for scientists working in the pharmaceutical industry. The authors take a practical approach and put the focus on the industrial aspects of the new QbD approach to pharmaceutical product development and manufacturing. The text covers quality risk management tools and analysis, applications of QbD to analytical methods, regulatory aspects, quality systems and knowledge management. In addition, the book explores the development and manufacture of drug substance and product, design of experiments, the role of excipients, multivariate analysis, and include several examples of applications of QbD in actual practice. This important resource: Covers the essential information about Quality by Design (QbD) that is at the heart of modern pharmaceutical development Puts the focus on the industrial aspects of the new QbD approach Includes several illustrative examples of applications of QbD in practice Offers advanced specialist topics that can be systematically applied to industry Pharmaceutical Quality by Design offers a guide to the principles and application of Quality by Design (QbD), the holistic approach to manufacturing that offers a complete understanding of the manufacturing processes involved, in order to yield consistent and high quality products.

Купить

Автор: Mark Rothstein A

Through analyses of the complex underlying issues, this interdisciplinary volume frames the agenda for dealing with genetic variation and incorporating pharmacogenomics into health care. The three sections of this book, Research Issues, Clinical Issues, and Social Perspectives address key elements integral to a comprehensive discussion of this emerging field. This groundbreaking text… Examines new research strategies, methodologies, and ethical and social considerations of pharmacogenomics Addresses practical considerations of anticipated changes in education, training, oversight, guidelines and protocols, and continuing education requirements Provides analyses of the potential enormous impact of pharmacogenomics, such as in the standard of care and treatment, including perspectives from the fields of anthropology, law, ethics, and economics

Купить

Автор: Группа авторов

Pharmacology for the Health Care Professions is an accessible introduction to the pharmacology necessary for health care professionals training to be non-medical prescribers looking for an overview of the subject. The book covers the pharmacology necessary for accredited training programmes in non-medical prescribing and certification in access and supply of prescription-only medicines and will be useful as an ongoing reference for future use in practice. Opening with a general introduction to pharmacology as a science, the book goes on to explain what is meant by drugs and medicines and why pharmacology should be of relevance to health care professionals. The reader is presented with general principles of pharmacology followed by systemic pharmacology that covers the actions of important groups of drugs in common use to treat diseases and conditions of the cardiovascular, respiratory, endocrine, musculoskeletal, skin and central nervous systems. The physiology and pathophysiology relevant to the understanding of how these drugs work is included. Finally the book explores the law in relation to the sale, supply, administration and prescription of drugs and explains what is meant by non-medical prescribing. All aspects of non-medical prescribing are considered including the use of exemptions to the Medicines Act, patient group directions, supplementary prescribing and the development of independent prescribing for nurses and pharmacists. Pharmacology is explained in simple, easy to understand terms and the book avoids any unnecessary chemistry where possible. Case studies that are of particular relevance to health care professionals are used throughout to illustrate the importance of the pharmacology major body systems and pathologies and the potential problems of adverse drug reactions and drug-drug interactions.

Купить

Автор: Hugo Kubinyi

This handbook is the first to address the practical aspects of this novel method. It provides a complete overview of the field and progresses from general considerations to real life scenarios in drug discovery research. Starting with an introductory historical overview, the authors move on to discuss ligand-based approaches, including 3D pharmacophores and 4D QSAR, as well as the concept and application of pseudoreceptors. The next section on structure-based approaches includes pharmcophores from ligand-protein complexes, FLIP and 3D protein-ligand binding interactions. The whole is rounded off with a complete section devoted to applications and examples, including modeling of ADME properties. With its critical evaluation of pharmacophore-based strategies, this book represents a valuable aid for project leaders and decision-makers in the pharmaceutical industry, as well as pharmacologists, and medicinal and chemists.

Купить

Автор: Gershon Samuel

This book fulfils an urgent need for an updated text on pediatric psychopharmacology. It takes a unique approach in discussing recent findings within the context of current issues, including economic and political ones. The book covers the emerging question of treating children who do not yet meet diagnostic criteria for psychosis, e.g, schizophrenia or bipolar disorder, but who are deemed to be at high risk. This is an active area of debate: such children are being treated in certain centers, while others reject this completely. The book addresses the antidepressant controversy, the placebo response and unique strategies for delineating this, and ways to optimize the differential between active medication and placebo. It reviews the impact of recent American Heart Association guidelines for monitoring children on stimulants and other psychotropics. It adheres closely to DSM-IV diagnostic criteria throughout. The book describes the use of newly approved drugs such as Lexapro for treating adolescent depression and the novel compound Intuniv. It covers the TADS and CAMS studies, which evaluated the use of SSRIs alone and in combination with cognitive behavioral therapy for adolescent depression. Other topics include treatment of bipolar disorders, the increasing popularity of generic equivalents, combination pharmacotherapy and the potential dangers of psychotropic medications. Third edition of the first ever book published on pediatric psychopharmacology from renowned editors. Incorporates current developments with regard to SSRIs, their indications and their safety issues, including possible associated suicidal behavior. Addresses concerns about cardiovascular side effects of the new stimulant medications available, and compares to other FDA-approved medications for ADHD. Features many tables, figures and pictorials, making it highly accessible and reader friendly.

Купить

Автор: Floyd Gardner M

A greatly revised and expanded account of phaselock technology The Third Edition of this landmark book presents new developments in the field of phaselock loops, some of which have never been published until now. Established concepts are reviewed critically and recommendations are offered for improved formulations. The work reflects the author's own research and many years of hands-on experience with phaselock loops. Reflecting the myriad of phaselock loops that are now found in electronic devices such as televisions, computers, radios, and cell phones, the book offers readers much new material, including: * Revised and expanded coverage of transfer functions * Two chapters on phase noise * Two chapters examining digital phaselock loops * A chapter on charge-pump phaselock loops * Expanded discussion of phase detectors and of oscillators * A chapter on anomalous phaselocking * A chapter on graphical aids, including Bode plots, root locus plots, and Nichols charts As in the previous editions, the focus of the book is on underlying principles, which remain valid despite technological advances. Extensive references guide readers to additional information to help them explore particular topics in greater depth. Phaselock Techniques, Third Edition is intended for practicing engineers, researchers, and graduate students. This critically acclaimed book has been thoroughly updated with new information and expanded for greater depth.

Купить

Автор: Philip Fisher A

A classic collection of titles from one of the most influential investors of all time: Philip A. Fisher Regarded as one of the pioneers of modern investment theory, Philip A. Fisher's investment principles are studied and used by contemporary finance professionals including Warren Buffett. Fisher was the first to consider a stock's worth in terms of potential growth instead of just price trends and absolute value. His principles espouse identifying long-term growth stocks and their emerging value as opposed to choosing short-term trades for initial profit. Now, for the first time ever, Philip Fisher Investment Classics brings together four classic titles, written by the man who is know as the «Father of Growth Investing.» Common Stocks and Uncommon Profits was the first investing book to reach the New York Times bestseller list. Outlining a 15-step process for identifying profitable stocks, it is one of the most influential investing books of all time Paths to Wealth Through Common Stocks, expands the innovative ideas in Fisher's highly regarded Common Stocks and Uncommon Profits, and explores how profits have been, and will continue to be made, through common stock ownership—asserting why this method can increase profits and reduce risk Also included is Conservative Investors Sleep Well and Developing an Investment Philosophy Designed with the serious investor in mind, Philip Fisher Investment Classics puts the insights of one of the greatest investment minds of our time at your fingertips.

Купить

Автор: Halpin Harry

This is the first interdisciplinary exploration of the philosophical foundations of the Web, a new area of inquiry that has important implications across a range of domains. Contains twelve essays that bridge the fields of philosophy, cognitive science, and phenomenology Tackles questions such as the impact of Google on intelligence and epistemology, the philosophical status of digital objects, ethics on the Web, semantic and ontological changes caused by the Web, and the potential of the Web to serve as a genuine cognitive extension Brings together insightful new scholarship from well-known analytic and continental philosophers, such as Andy Clark and Bernard Stiegler, as well as rising scholars in “digital native” philosophy and engineering Includes an interview with Tim Berners-Lee, the inventor of the Web

Купить

Автор: Кристофер Хэднеги

An essential anti-phishing desk reference for anyone with an email address Phishing Dark Waters addresses the growing and continuing scourge of phishing emails, and provides actionable defensive techniques and tools to help you steer clear of malicious emails. Phishing is analyzed from the viewpoint of human decision-making and the impact of deliberate influence and manipulation on the recipient. With expert guidance, this book provides insight into the financial, corporate espionage, nation state, and identity theft goals of the attackers, and teaches you how to spot a spoofed e-mail or cloned website. Included are detailed examples of high profile breaches at Target, RSA, Coca Cola, and the AP, as well as an examination of sample scams including the Nigerian 419, financial themes, and post high-profile event attacks. Learn how to protect yourself and your organization using anti-phishing tools, and how to create your own phish to use as part of a security awareness program. Phishing is a social engineering technique through email that deceives users into taking an action that is not in their best interest, but usually with the goal of disclosing information or installing malware on the victim's computer. Phishing Dark Waters explains the phishing process and techniques, and the defenses available to keep scammers at bay. Learn what a phish is, and the deceptive ways they've been used Understand decision-making, and the sneaky ways phishers reel you in Recognize different types of phish, and know what to do when you catch one Use phishing as part of your security awareness program for heightened protection Attempts to deal with the growing number of phishing incidents include legislation, user training, public awareness, and technical security, but phishing still exploits the natural way humans respond to certain situations. Phishing Dark Waters is an indispensible guide to recognizing and blocking the phish, keeping you, your organization, and your finances safe.

Купить

Автор: William Katz F

The clear and easy way to get a handle on the science of speech The science of how people produce and perceive speech, phonetics has an array of real-world applications, from helping engineers create an authentic sounding Irish or Canadian accent for a GPS voice, to assisting forensics investigators identifying the person whose voice was caught on tape, to helping a film actor make the transition to the stage. Phonetics is a required course among students of speech pathology and linguistics, and it's a popular elective among students of telecommunications and forensics. The first popular guide to this fascinating discipline, Phonetics For Dummies is an excellent overview of the field for students enrolled in introductory phonetics courses and an ideal introduction for anyone with an interest in the field. Bonus instructional videos, video quizzes, and other content available online for download on the dummies.com product page for this book.

Купить

Автор: Dolores Hiskes G

Teaches students of all ages the basics of phonics with a time-tested, foolproof method This tenth edition of the best-selling book teaches reading using sounds and spelling patterns. These sounds and patterns are introduced one at a time, and slowly built into words, syllables, phrases, and sentences. Simple step-by-step directions begin every lesson. Although originally designed for K-2 emergent readers, this award-winning book is also successfully being used with adolescent and adult learners, as well as second language learners and students with learning disabilities. Wise and humorous proverbs encourage virtues such as patience, perseverance, honesty, kindness, compassion, courage, and loyalty. Offers help for all students including those with learning disabilities or very short attention spans Includes extensive examples, word lists, and practice readings that are 100% decodable Uses a multisensory method that benefits all learning styles This bestselling, much-loved book offers a complete approach to teaching phonics and reading for a fraction of the cost of other programs.

Купить

Автор: Livius Cotarca

In this manual, the authors compare the range of applications for phosgene with that of the alternative compounds, dealing in detail with the possible uses of diphosgene, triphosgene, carbon dioxide, organic carbonates, oxalylchloride and many other alternative materials used in synthesis. However, they clearly point out those cases where phosgene continues to have the advantage. The result is a mine of information for synthetic chemists working in industry and academia faced with the question of where the toxic phosgene can be replaced by an unproblematic compound – including the safety phosgenation.

Купить

Автор: CIBA Foundation Symposium

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Купить

Автор: 1x.com

The inspiration you need to help improve your photography skills Well-known for their stunning world-class photography, 1x.com has worked with their most talented photographers to handpick 100 awe-inspiring images and provided the back-story and photographer's secrets that helped capture them. This book presents you with inspiration as well as underlying techniques that can help improve your photography skills immediately. Shares behind-the-scene stories of the featured photos from the photographers themselves, from their artistic vision to the technical details that went into each shot Offers clear, concise, and accessible descriptions for the ideas, vision, performance, setup, location, equipment, camera settings, lighting diagrams, and image editing methods of each amazing photo Photo Inspiration provides a unique combination of the final photograph with the tools and knowledge that made it possible, all of which are aimed at helping you meet your photographic potential.

Купить