зарубежная образовательная литература (страница 94)

Автор: Nick Graham

Whether you’re very experienced in running projects, or absolutely new to it, PRINCE2 can help you run your projects more effectively. Planning a PRINCE2 Project In a Day For Dummies is designed to give you a one-day steer into the essentials of running the Initiation stage of a PRINCE2 project. It focuses on just one process – Initiating a Project – and one theme – Plans. This quick, handy guide is essential reading for anyone undertaking a new PRINCE2 project and for those interested in learning more about how PRINCE2 can improve their projects. Open the book and find: Planning the work of your project Deciding on appropriate controls Working up a detailed Business Case Creating your PID or ‘Project Initiation Documentation’ Online resources include: Ten tips for a good business case PRINCE2 glossary Gallery of images from the book

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Автор: Michael Middaugh F

In this era of increasing pressure on higher education institutions for accountability, Planning and Assessment in Higher Education is an essential resource for college and university leaders and staff charged with the task of providing evidence of institutional effectiveness. Michael F. Middaugh, a noted expert in the field, shows how colleges and universities can successfully measure student learning and institutional effectiveness and use these results to create more efficient communications with both internal and external constituencies as well as promote institutional effectiveness to support student learning. «How can the assessment of institutional effectiveness be used to provide a solid foundation for planning? Middaugh has crafted a comprehensive, practical guide that also explains what accrediting agencies really want and need to know about these topics.» —Elizabeth H. Sibolski, executive vice president, Middle States Commission on Higher Education «Only Michael Middaugh, the unquestioned national leader in this field, could write such a lucid overview of how to make institutional assessment and planning really work as a tool rather than as a tedious requirement. He helped invent and shape the focus of national assessment rubrics and now offers his insights into how to make them work for your institution.» —John C. Cavanaugh, chancellor, Pennsylvania State System of Higher Education «Middaugh provides extremely helpful and practical guidance and insights on how colleges and universities can use assessment tools and frameworks to improve both academic programs and administrative operations. A valuable and timely book for all higher education leaders.» —James P. Honan, senior lecturer on education, Harvard Graduate School of Education

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Автор: Elkamel Ali

Clearly divided into three main sections, this practical book familiarizes readers with the area of planning in petroleum refining and petrochemical industry, while introducing several planning and modeling strategies encompassing single site refinery plants, multiple refinery networks, petrochemical networks, and refinery and petrochemical planning systems. It equally provides an insight into possible research directions and recommendations for the area of refinery and petrochemical planning. Furthermore, several appendices are included to explain the general background necessary, including stochastic programming, chance constraint programming, and robust optimization. For engineers and managers working in the petroleum industry as well as academic researchers in production, logistics, and supply chain management.

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Автор: Valdir Cechinel-Filho

An in-depth exploration of the applications of plant bioactive metabolites in drug research and development Highlighting the complexity and applications of plant bioactive metabolites in organic and medicinal chemistry, Plant Bioactives and Drug Discovery: Principles, Practice, and Perspectives provides an in-depth overview of the ways in which plants can inform drug research and development. An edited volume featuring multidisciplinary international contributions from acclaimed scientists researching bioactive natural products, the book provides an incisive overview of one of the most important topics in pharmaceutical studies today. With coverage of strategic methods of natural compound isolation, structural manipulation, natural products in clinical trials, quality control, and more, and featuring case studies on medicinal plants, the book serves as a definitive guide to the field of plant biodiversity as it relates to medicine. In addition, chapters on using natural products as drugs that target specific disease areas, including neurological disorders, inflammation, infectious diseases, and cancer, illustrate the myriad possibilities for therapeutic applications. Wide ranging and comprehensive, Plant Bioactives and Drug Discovery also includes important information on marketing, regulations, intellectual property rights, and academic-industry collaboration as they relate to plant-based drug research, making it an essential resource for advanced students and academic and industry professionals working in biochemical, pharmaceutical, and related fields.

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Автор: Jules Janick

Plant Breeding Reviews presents state-of-the-art reviews on plant breeding and genetics covering horticultural, agronomic and forestry crops, incorporating both traditional and molecular methods. The contributions are authored by world authorities, anonymously reviewed, and edited by Professor Jules Janick of Purdue University, USA. The series is an indispensible resource for crop breeders, plant scientists, and teachers involved in crop improvement and genetic resources. Initiated in 1983, Plant Breeding Reviews is published in the form of one or two volumes per year. Recently published articles include: Epigenetics and Plant Breeding (v30) Enhancing Crop Gene Pools with Beneficial Traits Using Wild Relatives (v30) Coffee Germplasm Resources, Genomics and Breeding (v30) Molecular Genetics and Breeding for Fatty Acid Manipulation in Soybean (v30) Breeding Southern Highbush Blueberries (v30) Development of Fire Blight Resistance by Recombinant DNA Technology (v29)

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Автор: Jules Janick

Plant Breeding Reviews presents state-of-the-art reviews on plant genetics and the breeding of all types of crops by both traditional means and molecular methods. Many of the crops widely grown today stem from a very narrow genetic base; understanding and preserving crop genetic resources is vital to the security of food systems worldwide. The emphasis of the series is on methodology, a fundamental understanding of crop genetics, and applications to major crops. The series is sponsored by the American Society for Horticultural Science and appears in the form of one or two volumes per year.

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Автор: Irwin Goldman

Plant Breeding Reviews presents state-of-the-art reviews on plant genetics and the breeding of all types of crops by both traditional means and molecular methods. Many of the crops widely grown today stem from a very narrow genetic base; understanding and preserving crop genetic resources is vital to the security of food systems worldwide. The emphasis of the series is on methodology, a fundamental understanding of crop genetics, and applications to major crops.

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Автор: Anthony Paul

The ability to culture cells is fundamental for mass propagation and as a baseline for the genetic manipulation of plant nuclei and organelles. The introduction to Plant Cell Culture: Essential Methods provides a general background to plant cell culture, including basic principles, technologies and laboratory practices that underpin the more detailed techniques described in subsequent chapters. Whilst each chapter provides a background to the topic area and methodology, a crucial aspect is the provision of detailed protocols with emphasis on trouble shooting, describing common problems and detailed advice for their avoidance. Plant Cell Culture: Essential Methods provides the reader with a concise overview of these techniques, including micropropagation, mutagenesis, cryopreservation, genetic and plastid transformation and somatic cell technologies. This book will be an essential addition to any plant science laboratory's bookshelf. Highlights the best and most up-to-date techniques for working on plant cell culture Explains clearly and precisely how to carry out selected techniques in addition to background information on the various approaches Chapters are written by leading international authorities in the field and cover both well-known and new, tried and tested, methods for working in plant cell culture An essential laboratory manual for students and early-career researchers.

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Автор: Jiang Jiming

Plant Centromere Biology is dedicated to plant centromere research. Chapters cover the structure of centromeres from several plant species including Arabidopsis thaliana, rice, maize, wheat and beet, while other sections cover several unique characteristics associated with plant centromeres, including classical and modern neocentromeres, centromere drive and centromere misdivision. Additional chapters are dedicated to epigenetic modification and evolution of plant centromeres, and development and application of plant artificial chromosomes. Written by an international group of experts in the field, Plant Centromere Biology is a valuable handbook for all plant scientists working on plant genome research. Beyond the bench, it can also serve as a helpful reference tool or textbook for upper level college classes on cytogenetics or genome analysis.

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Автор: Matthew Jenks A

Plant desiccation tolerance is of great basic and applied scientific interest. Understanding plant responses and adaptations to severe desiccation is key to applying desiccation tolerance research to the improvement of economically important crops. Plant Desiccation Tolerance brings together a field of international researchers to provide a current review of the advances in plant desiccation tolerance research. The book is broken up into three sections: Vegetative Desiccation Tolerance; Desiccation Tolerance of Pollen, Spores, and Seeds; and Applications of Desiccation Tolerance Research. Completely up-to-date and written by leading desiccation experts, Plant Desiccation Tolerance will be of great interest to plant researchers and plant and crop science professionals.

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Автор: Li Yi

Gene Containment provides a comprehensive look at genetically modified organisms and the strategies and implementation of key methods to gene containment. The book is divided into 5 parts: An Introduction that discusses the need for biotechnology and GMOs, Section 1 looks at the need for gene containment, Part II discusses varying strategies for gene containment, section III explores the assessment of gene containment approaches, and section IV covers the steps involved in implementing gene containment. Gene Containment will provide a thorough and up to date look at gene containment research and the needs for implementing new strategies in this arena.

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Автор: Группа авторов

Plant research has stood at the forefront of the genomics revolution. One of the first genome projects, the sequencing of the commonly used model organism Arabidopsis, has already yielded important results for the study of a broad array of crops such as corn and soybeans. With crop and food bioengineering only in its infancy, the need to understand the fundamental genetic mechanisms of plants will only become more pressing. A comprehensive guide to this fascinating area of genomics, Plant Genomics and Proteomics presents an integrated, broadly accessible treatment of the complex relationship between the genome, transcriptome, and proteome of plants. This clearly written text introduces the reader to the range of molecular techniques applicable to investigating the unique facets of plant growth, development, and response to the environment. Coverage includes: Functional and structural genomics addressed within the context of current techniques and challenges to come How to utilize DNA and protein sequence data Practical considerations for choosing and employing the most commonly available computer applications A review of applications for biotechnology, including genetic modification and defense against pathogens Bioinformatics tools and Web resources Numerous examples from the latest research throughout Assuming no specialized knowledge of plant biology on the part of its reader, Plant Genomics and Proteomics provides an invaluable resource for students and researchers in biotechnology, plant biology, genomics, and bioinformatics.

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Автор: Michael Morecroft D

Evidence grows daily of the changing climate and its impact on plants and animals. Plant function is inextricably linked to climate and atmospheric carbon dioxide concentration. On the shortest and smallest scales, the climate affects the plant’s immediate environment and so directly influences physiological processes. At larger scales, the climate influences species distribution and community composition, as well as the viability of different crops in managed ecosystems. Plant growth also influences the local, regional and global climate, through the exchanges of energy and gases between the plants and the air around them. Plant Growth and Climate Change examines the major aspects of how anthropogenic climate change affects plants, focusing on several key determinants of plant growth: atmospheric CO2, temperature, water availability and the interactions between these factors. The book demonstrates the variety of techniques used across plant science: detailed physiology in controlled environments; observational studies based on long-term data sets; field manipulation experiments and modelling. It is directed at advanced-level university students, researchers and professionals across the range of plant science disciplines, including plant physiology, plant ecology and crop science. It will also be of interest to earth system scientists.

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Автор: Martin Broadley R

A ‘textbook’ plant typically comprises about 85% water and 13.5% carbohydrates. The remaining fraction contains at least 14 mineral elements, without which plants would be unable to complete their life cycles. Understanding plant nutrition and applying this knowledge to practical use is important for several reasons. First, an understanding of plant nutrition allows fertilisers to be used more wisely. Second, the nutritional composition of crops must be tailored to meet the health of humans and livestock. Third, many regions of the world are currently unsuitable for crop production, and an understanding of plant nutrition can be used to develop strategies either for the remediation of this land or for the cultivation of novel crops. That application of knowledge of plant nutrition can be achieved through genotypic or agronomic approaches. Genotypic approaches, based on crop selection and / or breeding (conventional or GM), have recently begun to benefit from technological advances, including the completion of plant genome sequencing projects. This book provides an overview of how plant nutritional genomics, defined as the interaction between a plant's genome and its nutritional characteristics, has developed in the light of these technological advances, and how this new knowledge might usefully be applied. This is a book for researchers and professionals in plant molecular genetics, biochemistry and physiology, in both the academic and industrial sectors.

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Автор: IUBMB

A collection of current knowledge of phytochemicals and health Interest in phenolic phytochemicals has increased as scientific studies indicate these compounds exhibit potential health benefits. With contributions from world leaders in this research area, Plant Phenolics and Human Health: Biochemistry, Nutrition, and Pharmacology offers an essential survey of the current knowledge on the capacity of specific micronutrients present in ordinary diets to fight disease. The coverage in this resource: Explains the presence and biochemical properties of phenolics present in fruits and vegetables, as well as in foods derived from their plant sources Provides biochemical explanations on how certain plant phenolics fight cardiovascular and neurodegenerative diseases, cancer, and other widespread pathologies Focuses on certain phenolics, e.g., flavonoids, stilbenes, and curcuminoids, and provides insights on the biochemical bases used to define their significance in the diet as well as their recommended consumption requirements and toxicity Appropriate for graduate and upper-level undergraduate courses in human and animal nutrition, basic nutritional biology, physiology, pharmacology, and other health-related disciplines, Plant Phenolics and Human Health: Biochemistry, Nutrition, and Pharmacology serves as both an invaluable supplementary classroom text and a self-teaching guide for professionals interested in defining the association between diet and health from classical, alternative, and complementary biomedical perspectives.

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Автор: David Evered

Concern about the environmental consequences of the widespread use of pesticides has increased, and evidence of pesticide-resistant virus vectors have continued to emerge. This volume presents a timely survey of the mechanisms of plant resistance and examines current developments in breeding for resistance, with particular emphasis on advances in genetic engineering which allow for the incorporation of viral genetic material into plants. Discusses the mechanisms of innate resistance in strains of tobacco, tomato, and cowpea; various aspects of induced resistance, including the characterization and roles of the pathogenesis-related proteins; antiviral substances and their comparison with interferon; and cross-protection between plant virus strains. Also presents several papers which evaluate the status of genetic engineering as it relates to breeding resistant plants. Among these are discussions of the potential use of plant viruses as gene vectors, gene coding for viral coat protein, satellite RNA, and antisense RNA, and practical issues such as the durability of resistant crop plants in the field.

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Автор: Timothy Flowers J

This book provides a broad overview of solute transport in plants. It first determines what solutes are present in plants and what roles they play. The physical bases of ion and water movement are considered. The volume then discusses the ways in which solutes are moved across individual membranes, within and between cells, and around the plant. Having dealt with the role of plant solutes in ‘normal’ conditions, the volume proceeds to examine how the use of solutes has been adapted to more extreme environments such as hot, dry deserts, freezing mountains and saline marshes. A crucial stage in the life cycle of most plants, the internally-controlled dehydration concomitant with seed formation, is also addressed. Throughout the volume the authors link our increasing understanding of the cellular and molecular bases of solute movement with the roles that these fulfil in the whole plant under both ideal and stressful conditions, showing how these are dictated by the physical laws that govern solute and water movement. The book is directed at postgraduates, researchers and professionals in plant physiology, biochemistry and molecular biology.

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Автор: Nina Fedoroff V

The transposable genetic elements, or transposons, as they are now known, have had a tumultuous history. Discovered in the mid-20th century by Barbara McClintock, they were initially received with puzzlement. When their genomic abundance began to be apparent, they were categorized as «junk DNA» and acquired the label of parasites. Expanding understanding of gene and genome organization has revealed the profound extent of their impact on both. Plant Transposons and Genome Dynamics in Evolution captures and distills the voluminous research literature on plant transposable elements and seeks to assemble the big picture of how transposons shape gene structure and regulation, as well as how they sculpt genomes in evolution. Individual chapters provide concise overviews of the many flavors of plant transposons and of their roles in gene creation, gene regulation, development, genome evolution, and organismal speciation, as well as of their epigenetic regulation. This volume is essential reading for anyone working in plant genetics, epigenetics, or evolutionary biology.

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Автор: Iqbal Ahmad

Here, an extremely experienced team of authors from five different continents provides a timely review of progress in the use and exploitation of soil bacteria to improve crop and plant growth. They present novel ideas on how to grow better, more successful crops, in an environmentally sound way, making this invaluable reading for those working in the pharmaceutical, biotechnological and agricultural industries.

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Автор: Efim Oks

This book fills the gap for a textbook describing this kind of electron beam source in a systematic and thorough manner: from physical processes of electron emission to examples of real plasma electron sources and their applications.

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Автор: Boris Smirnov M

This problems supplement to plasma physics textbooks covers plasma theory for both science and technology. Written by a renowned plasma scientist, experienced book author and skilled teacher, it treats all aspects of plasma theory in no fewer than 520 very detailed worked-out problems. With this systematic collection the reader will gain a sound understanding of plasma physics in all fields, from fusion and astrophysics to surface treatment. The book also includes the transport of particles as well as radiation in plasmas, and while designed for graduate students and young researchers, it can equally serve as a reference.

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Автор: Группа авторов

This is the first book specializing in plasmids and their biomedical use, including all relevant aspects of production, applications, quality, and regulations. Readers will discover clinical applications for the wide range of preventive and therapeutic applications using plasmid DNA. The book describes modified vector systems based on plasmids, as well as the potency of genomic research and vector design by informatics. Using the example of fish vaccination, the application of DNA vaccination in veterinary health care is reviewed, followed by a detailed overview of plasmid production technology on an industrial scale. Finally, the book considers regulatory and quality assurance aspects of such new drugs plus thire market potential.

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Автор: A. Baner L

Plastics are the most important class of packaging materials. This successful handbook, now in its second edition, covers all important aspects of plastic packaging and the interdisciplinary knowledge needed by food chemists, pharmaceutical chemists, food technologists, materials scientists, process engineers, and product developers alike. This is an indispensable resource in the search for the optimal plastic packaging. Materials characteristics, additives and their effects, mass transport phenomena, quality assurance, and recent regulatory requirements from FDA and European Commission are covered in detail with ample data.

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Автор: A. Baner L

Plastics have developed into the most important class of packaging materials. Their relative impermeability for substances from the surroundings has great influence on the shelf life and the quality of the packed goods. At the same time the interaction between the contents and the various components of the packaging plays a decisive role. This particular book is indispensable in the search for the optimal plastic packaging. It facilitates the estimation of the influence on the goods which come from the surroundings and from the packaging. The authors do not restrict themselves only to the description of the phenomena of diffusion or transport in theory, but they show what they mean for practical applications. Food represents the central theme as main area of application for plastic packaging. It can be considered to be the «model substance» and the findings are to be applied to many other products and systems. The main rules and regulations for food packaging of the European Community and the United States are presented in this book. Furthermore the authors emphasize the testing methods for proving the mass transport and the sensory check of the quality of the products.

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Автор: Prof. Schwedt Georg

From natural rubber to fully synthetic polymers like nylon and teflon and up to biodegradable yoghurt cups: Georg Schwedt shows the whole spectrum of plastics, their development and applications as well as their influence on our daily life.

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Автор: Garc?a-Alonso ?ngel

The purpose of the book is to introduce platelets, and their functional role in thrombotic and cardiovascular disease, justifying the relevance of platelet proteomics research. Focus then shifts to the recent developments on mass spectrometry (MS)-based proteomics. This chapter shows potential applications for platelet proteomics not yet carried out. It includes examples of post-translational modifications (PTMs) analysis in platelets. The second part of the book focuses on the main research done so far on platelet proteomics. This includes general proteome mapping by non-gel based separation methods (MudPit), analysis of the general platelet proteome and signaling cascades by gel-based separation methods (2-DE), sub-proteome analyses (secretome/releasate, membrane proteins, organelles). Finally, the last section links the platelet transcriptome and application to disease. This section is highly relevant and includes chapters on proteomics, transcriptomics, functional genomics, systems biology, and their applications to platelet-related diseases.

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Автор: Джон Гришэм

Rick Dockery was the third-string quarterback for the Cleveland Browns. In the deciding game at the climax of the season, to the surprise and dismay of virtually everyone, Rick actually got into the game. With a 17-point lead and just minutes to go, Rick provided what was arguably the worst single performance in the history of the NFL. Overnight, he became a national laughing stock and, of course, was immediately dropped by the Browns and shunned by all other teams. But all Rick knows is football, and he insists that his agent, Arnie, finds a team that needs him. Against enormous odds, Arnie finally locates just such a team and informs Rick that, miraculously, he can in fact now be a starting quarterback. Great says Rick – for which team?The mighty Panthers of Parma, Italy.Yes, Italians do play American football, to one degree or another, and the Parma Panthers desperately want a player from the home of American footballat their helm. So Rick reluctantly agrees to play for the Panthers – at least until a better offer comes along – and heads off to Italy. He knows nothing about Parma (not even where it is), has never been to Europe, and doesn't speak or understand a word of Italian. To say that Italy – the land of opera, fine wines, extremely small cars, romance and football americano – holds a few surprises for Rick Dockery would be something of an understatement.

Исполнители: Christopher Evan Welch

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Автор: Norbert Lechner M

Discover sustainable methods for designing crucial building systems for architects. This indispensable companion to Norbert Lechner's landmark volume Heating, Cooling, Lighting: Sustainable Design Methods for Architects, Third Edition completes the author's mission to cover all topics in the field of sustainable environmental control. It provides knowledge appropriate for the level of complexity needed at the schematic design stage and presents the most up-to-date information available in a concise, logical, accessible manner and arrangement. Although sustainability deals with many issues, those concerning energy and efficiency are the most critical, making an additional goal of this book one of providing architects with the skills and knowledge needed to create buildings that use electricity and water efficiently. Guidelines and rules-of-thumb are provided to help designers make their buildings use less energy, less water, and less of everything else to achieve their primary objectives. In addition, this book: Addresses ways to reduce electricity usage through more efficient lighting systems and appliances and by incorporating automatic switches and control systems that turn off systems not in use. Covers the design of well-planned effluent treatment systems that protect against potential health hazards while also becoming a valuable source of reclaimed water and fertilize.r Provides coverage of fire protection and conveyance systems, including very efficient types of elevators and escalators and designs that encourage the use of stairs or ramps. Complete with case studies that illustrate how these systems are incorporated into large-project plans, Plumbing, Electricity, Acoustics is an indispensable resource for any architect involved in a sustainable design project.

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Автор: Charles Duncan

A unique learning resource to prepare for the PMP® certification exam Without sufficient practice and preparation for taking the Project Management Institute's (PMI's) PMP® certification exam, you won't be able to actually put your skills into practice in the real world! To help you achieve your goal of passing the exam, this two-part prep book covers all elements of the brand-new Project Management Professional exam. A team of experts presents you with a solid overview of the exam as well as hundreds of questions, detailed answers, and explanations. In addition, each question is accompanied by cross-references, providing you with a thorough preparation foundation for taking the PMP® exam. Features hundreds of short questions-and-answers on some of the most key topics that PMPs should be familiar with before taking the exam Includes more than 800 exam-quality questions with detailed answers and explanations, plus more than 200 fill-in-the-blank, true/false, and short answer questions to help you prepare for the exam Serves as an ideal complement to Sybex's PMP®: Project Management Professional Exam Study Guide, 6th Edition PMP® Practice Makes Perfect prepares you for taking the grueling 200-question, four-hour PMP® exam. (PMBOK, PMI, PMP and Project Management Professional are registered marks of the Project Management Institute, Inc.)

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Автор: Группа авторов

Polarized Light in Liquid Crystals and Polymers deals with the linear optics of birefringent materials, such as liquid crystals and polymers, and surveys light propagation in such media with special attention to applications. It is unique in treating light propagation in micro- and nanostructured birefringent optical elements, such as lenses and gratings composed of birefringent materials, as well as the spatial varying anisotropic structures often found in miniaturized liquid crystal devices.

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Автор: Группа авторов

In this carefully researched, thought-provoking book, Geoffrey Hughes examines the trajectory of political correctness and its impact on public life. Focusing on the historical, semantic, and cultural aspects of political correctness, it will intrigue anyone interested in this ongoing debate. A unique and intriguing journey through the trajectory of political correctness and its impact on public life, focusing on the historical, semantic, and cultural aspects of what PC means Explores the origins, progress, content and style of political correctness, discussing and analyzing around one hundred terms and lexical formations, from Chaucer and Shakespeare, Marlowe and Swift, to nursery rhymes, rap and Spike Lee films, David Mamet, J. M. Coetzee and Philip Larkin Offers a detailed semantic analysis of the way that key words have been exploited both to advance the agendas of political correctness and to refute them

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Автор: Kevin Cox R

Developed out of the author's own substantial teaching experience, this introduction to political geography approaches its subject matter from the standpoint of political economy and the politics of difference.

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Автор: STREECK WOLFGANG

In a world of increasing austerity measures, democratic politics comes under pressure. With the need to consolidate budgets and to accommodate financial markets, the responsiveness of governments to voters declines. However, democracy depends on choice. Citizens must be able to influence the course of government through elections and if a change in government cannot translate into different policies, democracy is incapacitated. Many mature democracies are approaching this situation as they confront fiscal crisis. For almost three decades, OECD countries have – in fits and starts – run deficits and accumulated debt. As a result, an ever smaller part of government revenue is available today for discretionary spending and social investment and whichever party comes into office will find its hands tied by past decisions. The current financial and fiscal crisis has exacerbated the long-term shrinking government discretion; projects for political change have lost credibility. Many citizens are aware of this situation: they turn away from party politics and stay at home on Election Day. With contributions from leading scholars in the forefront of sociology, politics and economics, this timely book will be of great interest to students and scholars throughout the social sciences as well as general readers.

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Автор: Группа авторов

This is the first book to describe the synthesis and characterization of the materials used in polymer-supported synthesis. The authors cover not only the classical polymers and their use in homogeneous, heterogeneous and micellar catalysis, but also such new developments as «enzyme-labile linkers», illustrating how to simplify the purification process and avoid waste. The result is a wealth of useful information – for beginners and experts alike – in one handy reference, removing the need for difficult and time-consuming research among the literature.

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Автор: Hongting Pu

Including chemical, synthetic, and cross-disciplinary approaches; this book includes the necessary techniques and technologies to help readers better understand polymers for polymer electrolyte membrane (PEM) fuel cells. The methods in the book are essential to researchers and scientists in the field and will lead to further development in polymer and fuel cell technologies. • Provides complete, essential, and comprehensive overview of polymer applications for PEM fuel cells • Emphasizes state-of-the-art developments and methods, like PEMs for novel fuel cells and polymers for fuel cell catalysts • Includes detailed chapters on major topics, like PEM for direct liquid fuel cells and fluoropolymers and non-fluorinated polymers for PEM • Has relevance to a range of industries – like polymer engineering, materials, and green technology – involved with fuel cell technologies and R&D

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Автор: Leno Mascia

We are surrounded by polymers: Whether it's to prepare a meal, use computer keyboards and mousepads, or step onto a new playground, you'll encounter a plastic product made of polymers. Owing to the extraordinary range of properties accessible in polymeric materials, they play an essential and ubiquitous role in everyday life – from plastics and elastomers on the one hand to natural biopolymers such as DNA and proteins that are essential for life on the other. This desktop and library reference book provides a comprehensive yet concise overview of the materials, manufacture, structure and architecture, properties, processing, and applications of withing the field of polymers. The book offers a unique mix of theory and application, the essential personal reference for anyone studying or working within the field of polymers.

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Автор: Rolf Hilfiker

Polymorphism in the Pharmaceutical Industry – Solid Form and Drug Development highlights the relevance of polymorphism in modern pharmaceutical chemistry, with a focus on quality by design (QbD) concepts. It covers all important issues by way of case studies, ranging from properties and crystallization, via thermodynamics, analytics and theoretical modelling right up to patent issues. As such, the book underscores the importance of solid-state chemistry within chemical and pharmaceutical development. It emphasizes why solid-state issues are important, the approaches needed to avoid problems and the opportunities offered by solid-state properties. The authors include true polymorphs as well as solvates and hydrates, while providing information on physicochemical properties, crystallization thermodynamics, quantum-mechanical modelling, and up-scaling. Important analytical tools to characterize solid-state forms and to quantify mixtures are summarized, and case studies on solid-state development processes in industry are also provided. Written by acknowledged experts in the field, this is a high-quality reference for researchers, project managers and quality assurance managers in pharmaceutical, agrochemical and fine chemical companies as well as for academics and newcomers to organic solid-state chemistry.

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Автор: CIBA Foundation Symposium

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

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Автор: Jens-Uwe Peters

An essential outline of the main facets of polypharmacology in drug discovery research Extending drug discovery opportunities beyond the «one drug, one target» philosophy, a polypharmacological approach to the treatment of complex diseases is emerging as a hot topic in both industry and academic research. Polypharmacology in Drug Discovery presents an overview of the various facets of polypharmacology and how it can be applied as an innovative concept for developing medicines for treating bacterial infections, epilepsy, cancer, psychiatric disorders, and more. Filled with a collection of instructive case studies that reinforce the material and illuminate the subject, this practical guide: Covers the two-sided nature of polypharmacology—its contribution to adverse drug reactions and its benefit in certain therapeutic drug classes Addresses the important topic of polypharmacology in drug discovery, a subject that has not been thoroughly covered outside of scattered journal articles Overviews state-of-the-art approaches and developments to help readers understand concepts and issues related to polypharmacology Fosters interdisciplinary drug discovery research by embracing computational, synthetic, in vitro and in vivo pharmacological and clinical aspects of polypharmacology A clear road map for helping readers successfully navigate around the problems involved with promiscuous ligands and targets, Polypharmacology in Drug Discovery provides real examples, in-depth explanations and discussions, and detailed reviews and opinions to spark inspiration for new drug discovery projects.

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Автор: Группа авторов

Brings together, analyzes, and contextualizes the latest findings and practical applications Polyphosphazenes, an emerging class of polymers, include macromolecules, which have been proven to be biocompatible, biodegradable, and bioactive. Their unprecedented structural diversity and unique properties make them suitable as vaccine adjuvants, microencapsulating agents, biodegradable materials, scaffolds for tissue engineering, biocompatible coatings, and carriers for gene delivery. Polyphosphazenes for Biomedical Applications offers a thorough review of polyphosphazene research findings in the life sciences, chemistry, and chemical engineering. It emphasizes biomedical applications as well as recent advances in polyphosphazene development such as high-throughput discovery and the latest controlled methods of synthesis. The book brings together, analyzes, and contextualizes a wealth of knowledge that previously could only be found scattered throughout the scientific literature. Following two introductory chapters, the book reviews: Vaccine delivery and immunomodulation Biomaterials Drug delivery systems Biodetection Well-defined polyphosphazenes: synthetic aspects and novel molecular architectures All the chapters have been written by leading researchers in the field. Editor Alexander Andrianov, who has led the effort to commercialize polyphosphazenes for biomedical applications, has carefully reviewed and edited all chapters to ensure readability, accuracy, and thoroughness. Polyphosphazenes for Biomedical Applications is not only intended for researchers working in polyphosphazene chemistry, but also for all researchers seeking solutions to problems arising in the areas of biomaterials, drug delivery systems, and controlled release formulations.

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Автор: Chen Z. Jeffrey

Polyploidy plays an important role in biological diversity, trait improvement, and plant species survival. Understanding the evolutionary phenomenon of polyploidy is a key challenge for plant and crop scientists. This book is made up of contributions from leading researchers in the field from around the world, providing a truly global review of the subject. Providing broad-ranging coverage, and up-to-date information from some of the world’s leading researchers, this book is an invaluable resource for geneticists, plant and crop scientists, and evolutionary biologists.

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Автор: Группа авторов

This book provides a comprehensive review of the chemistry and research illustrating the benefits of polyurethane for immobilizing cells, with dozens of case studies in medical devices and environmental engineering. • Offers an essential resource for medical and environmental scientists • Provides a multidisciplinary and lucid writing style that uses little or no jargon • Extrapolates current technology into advanced areas, especially environmental remediation and medical devices • Fills the gap between immobilization research and practical applications

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Автор: Nicholas Leider

Practical, step-by-step tips for players of all levels From Snooker to Carom to good-old-fashioned 8- or 9-Ball, Pool & Billiards For Dummies reveals the tips, tricks, and rules of play, covering the variety of the ever-popular games that make up pool and billiards. This hands-on guide discusses everything from the rules and strategies of the games to how to set up a pool room to choosing the right equipment, and is accompanied by dozens of photos and line drawings. See how hard to hit the cue ball and where to hit it, the angle to hold the cue stick and how much chalk to use, how to use a bridge, and how to put spin on the ball Includes advanced pool techniques and trick shots for the seasoned pool sharp With Pool & Billiards For Dummies, even a novice can play like a champion!

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Автор: Alan Templeton R

The advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics. Population Genetics and Microevolutionary Theory takes a modern approach to population genetics, incorporating modern molecular biology, species-level evolutionary biology, and a thorough acknowledgment of quantitative genetics as the theoretical basis for population genetics. Logically organized into three main sections on population structure and history, genotype-phenotype interactions, and selection/adaptation Extensive use of real examples to illustrate concepts Written in a clear and accessible manner and devoid of complex mathematical equations Includes the author's introduction to background material as well as a conclusion for a handy overview of the field and its modern applications Each chapter ends with a set of review questions and answers Offers helpful general references and Internet links

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Автор: Pete Harpum

This book describes the way that pharmaceutical projects and programs are currently managed, and offers views from many highly experienced practitioners from within the industry on future directions for drug program management. The book integrates portfolio, program, and project management processes as fundamental for effective and efficient drug product development. Contributing expert authors provide their view of how the projectization approach can be taken forward by the drug industry over the coming years.

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Автор: Jack Reigle

An essential guide for a firm of any size to effectively position itself in the marketplace For an architecture or design firm to survive and prosper in the new economy, it needs to redefine and reinvigorate its position in the marketplace. With dozens of how-to cases, examples, and guidelines, Positioning for Architecture and Design Firms provides the entire menu of tools, plus the inspiration needed, for making the changes required to stay competitive in the design world. Offering strategies for leveraging a firm's strongest assets into the formulation of a successful long-term plan, this book breaks with tradition to introduce the latest concepts specifically developed for building future business opportunities in an unstable economic landscape marked by shifts in competition, technology, and client expectations. With a wealth of information targeting the subject of positioning, readers will learn: Why the aftershocks of the Great Recession are likely to linger, and what you can do about it in relation to your firm's success How the coming generational shift will change the design business What positioning is, and how it needs to be developed to support and implement your strategic vision How your firm can establish a robust identity and operating model The importance of your firm's essential purpose How to turn your marketing department into a true marketing system, transforming it from production mode into an integrated positioning machine Why it is important to engage in advanced research and open innovation initiatives Addressing issues of firm identity, including an understanding of how to create the market positioning desired, Positioning for Architecture and Design Firms shows how a design firm—large or small, new or well established—can position itself to gain greater control over its destiny, and reach loftier levels of achievement. Learn about firm types, and match the right type to a firm's goals Develop and maintain a firm's identity in the marketplace Discover how organizational design and marketing support a chosen firm type

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Автор: Jeffrey L. Buller

A book that every academic leader should read and put into practice. —Kim Cameron, associate dean of executive education, Ross School of Business, University of Michigan Praise for Positive Academic Leadership « Buller has produced a book that every academic leader should read and put into practice. Positive Academic Leadership pulls together an amazing array of scientific findings and practical guidelines that will be invaluable for academic leaders looking to improve themselves and their institutions.» – Kim Cameron, associate dean, William Russell Professor of Management and Organizations, Ross School of Business; professor of higher education, School of Education, University of Michigan « If I had a magic wand and could make one wish for all of higher education, it would be that we had better institutional leadership. Whether one is a chair, dean, provost, president, or on the Board of Trustees, this book can make a world of difference in your ability to provide that leadership!» – L. Dee Fink, author, Creating Significant Learning Experiences; former president, Professional and Organizational Development Network in Higher Education « Buller's book brings hope for leadership in higher education by emphasizing the importance of a positive approach that empowers and inspires others. Positive Academic Leadership has the potential to transform higher education for the benefit of students, faculty, and ultimately our communities and our world.» – Kina S. Mallard, provost and vice president of academic affairs, Carson-Newman University « Academic leaders who find themselves engulfed in negative thinking and considering only damage control scenarios for pressing issues will want to read this book. Employing what Jeffrey Buller calls 'positive academic leadership' is, I believe, essential to transforming feelings of despair into constructive leadership.» – Mary Lou Higgerson, vice president for academic affairs, emerita, Baldwin Wallace University « I can't recall reading any book on leadership that is more applicable to the work of faculty development. Every academic leader—faculty member, chair, dean, or campus administrator—will benefit from Jeffrey Buller's evidence-based model and practices of positive academic leadership.» – Mary Deane Sorcinelli, associate provost for faculty development, University of Massachusetts Amherst

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Автор: Vasilenko Sara A

Developing healthy sexual behaviors is critical to adolescents’ wellbeing. While more emphasis has been on negative outcomes, there are broad positive implications for physical health, mental health, intimate relationships, and identity development. To fully understand the impact, we need to understand both. In addition, the impact of sexual behavior is not universal, but may differ based on individuals’ demographic, relational, contextual, and attitudinal factors. This volume provides a framework for understanding the complex role of sexual behavior in adolescents’ lives, with a specific focus on the roles of sexual minority status, internet-based sexual experiences, relationship context, and sexual learning through formal and informal sex education in determining the outcomes of sexual behavior. It provides: A nuanced, multidimensional understanding of the role of sexual behavior in shaping adolescents’ development and well-being Important directions for future research Recommendations for sexuality education, prevention, and intervention programs. This is the 144th volume in this Jossey-Bass series New Directions for Child and Adolescent Development. Its mission is to provide scientific and scholarly presentations on cutting edge issues and concepts in this subject area. Each volume focuses on a specific new direction or research topic and is edited by experts from that field.

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Автор: Donna Wilson

Positively Smarter brings together seven principles for connecting the science of neuroplasticity to practical strategies for enhancing the synergy of happiness, achievement, and physical well-being. Moving beyond common myths, the text builds an evidence-based paradigm to empower readers to take practical steps to move forward. Brings together current research on cognitive psychology, education (learning), and implications of neuroscience to suggest powerful ways to enhance the kind of cognitive function and productivity that leads to happiness and success Applies implications of current research showing that happiness is a skill and that positive affect can lead to higher levels of creative problem solving, productivity, achievement, and well-being Shares research and strategies for supporting physical activity and nutrition that may enhance neuroplasticity, cognitive performance, and positive affect Puts learners first and then brings in the science, presenting creative or adaptive strategies that can be applied in the real world Includes action assessments to guide readers in taking concrete steps to achieve the goals they set for themselves Identifies deeply held assumptions that innate talent, genes, socioeconomic status, and ethnicity mean that a significant percentage of the population lacks the neurocognitive potential to achieve at higher levels Draws on the authors’ research from a broad range of fields in order to maximize the positive impact of a synergistic approach

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Автор: Группа авторов

Shows the diversity and sophistication of present knowledge of molecular collisions and the forces that govern their outcome, examining major aspects from the point of view of the potential surface. Covers such topics as angle dependent potentials, vibranic coupling, and branching ratios in simple atomic reactions.

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Автор: Alexander Emanuel Eigeles

Professor Emanuel uses clear presentation to compare and facilitate understanding of two seminal standards, The IEEE Std. 1459 and The DIN 40110-2:2002-11. Through critical analysis of the most important and recent theories and review of basic concepts, a highly accessible guide to the essence of the standards is presented. Key features: Explains the physical mechanism of energy flow under different conditions: single- and three-phase, sinusoidal and nonsinusoidal, balanced and unbalanced systems Starts at an elementary level and becomes more complex, with six core chapters and six appendices to clarify the mathematical aspects Discusses and recommends power definitions that played a significant historical role in paving the road for the two standards Provides a number of original unsolved problems at the end of each chapter Introduces a new nonactive power; the Randomness power. Power Definitions and the Physical Mechanism of Power Flow is useful for electrical engineers and consultants involved in energy and power quality. It is also helpful to engineers dealing with energy flow quantification, design and manufacturing of metering instrumentation; consultants working with regulations related to renewable energy courses and the smart grid; and electric utility planning and operation engineers dealing with energy bill structure. The text is also relevant to university researchers, professors, and advanced students in power systems, power quality and energy related courses.

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